The Electrolyte Therapy of Premenstrual Distress

Greenhill, J.P.

doi:10.1001/jama.1941.02820330008003

Cited by 40 publications

(8 citation statements)

References 8 publications

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“…[1920] It is well known that low magnesium levels result in the constriction of cerebral and abdominal blood vessels. [21] It is, thus, also possible that the water retention (bloating) that occurs during the luteal phase results, in part, from a slight increase in the constriction of the renal arterial vessels.…”

Section: Discussionmentioning

confidence: 99%

Changes in serum calcium, magnesium and inorganic phosphorus levels during different phases of the menstrual cycle

Dullo

Vedi

2008

J Hum Reprod Sci

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Background:The menstrual cycle is a complex process involving the interaction of the hypothalamus, the anterior pituitary, the ovaries and the uterus. The hormonal changes occurring during this cyclic process not only affect oocyte maturation and the endometrial and vaginal environments but can also have an effect on a number of other physiological and biochemical phenomena.Aim and Method:We investigated the changes in serum calcium, magnesium and inorganic phosphorus levels during different phases of the menstrual cycle in fifty healthy young women. We found subtle but significant variations in these levels in the menstrual, follicular and luteal phases.Result:The serum calcium level was highest in the follicular phase whereas the serum magnesium level was lowest in the follicular phase; the serum inorganic phosphorus levels was highest in the menstrual phase.Conclusion:These variations could be due to the impact of the changing estrogen and progesterone secretion on the parathyroid glands.

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Section: Discussionmentioning

confidence: 99%

Changes in serum calcium, magnesium and inorganic phosphorus levels during different phases of the menstrual cycle

Dullo

Vedi

2008

J Hum Reprod Sci

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“…Both an abnormal oestrogen/ progesterone ratio (12,16) and progesterone (6) have been suggested as caus ative factors. Water and sodium retention have also been implicated as the actual cause of the syndrome by Greenhill and Freed (11) and psychodynamic models have been suggested by Paulson (17).…”

mentioning

confidence: 99%

Correlation of Symptoms in Pre-Menstrual Tension to Oestrogen and Progesterone Concentrations in Blood Plasma

Bäckström

Mattsson

1975

Neuropsychobiology

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15 women with premenstrual tension are rated in four symptom groups, anxiety-tension, asthenia-depression, irritability-explosiveness and feelings of swelling. The ratings of anxiety and irritability were also added to a separate group. Ratings were then correlated to plasma oestrogen and progesterone levels and oestrogen/progesterone ratios. There was a significant correlation between oestrogen levels and the anxiety, irritability, anxiety + irritability and depression groups. A correlation was also found between oestrogen/progesterone ratios and anxiety. No significant correlation was found between progesterone levels and symptom ratings.

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“…Whilst authors on the subject of premenstrual tension have laid special emphasis on the possible endocrine causes for this condition (Frank, 1931; Israel, 1938; Greenblatt, 1940; Greenhill and Freed, 1941; Morton, 1950) the suggestion that it may be largely or entirely a psychogenic disturbance has received support from the fact that subjects of this complaint not infrequently are psychologically unstable and come from psychologically unstable families. When we are dealing with an event like menstruation, the advent of which is expected by the patient, such an explanation is difficult to disprove.…”

Section: Discussionmentioning

confidence: 99%

Mittelwahn

Geiringer

1951

BJOG

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The Electrolyte Therapy of Premenstrual Distress

Cited by 40 publications

References 8 publications

Changes in serum calcium, magnesium and inorganic phosphorus levels during different phases of the menstrual cycle

Changes in serum calcium, magnesium and inorganic phosphorus levels during different phases of the menstrual cycle

Correlation of Symptoms in Pre-Menstrual Tension to Oestrogen and Progesterone Concentrations in Blood Plasma

Mittelwahn

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