The Eleventh ENBDC Workshop: Advances in Technology Help to Unveil Mechanisms of Mammary Gland Development and Cancerogenesis

Vafaizadeh, Vida; Peuhu, Emilia; Mikkola, Marja L.; Khaled, Walid T.; Bentires‐Alj, Mohamed; Koledová, Zuzana

doi:10.1007/s10911-019-09436-0

Cited by 2 publications

(2 citation statements)

References 36 publications

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“…The European network of breast development and cancer (ENBDC) organizes an annual workshop on methods in mammary gland biology and breast cancer. This threeday meeting has been hosted every year until now in the charming small town Weggis in Switzerland [1], but the twelfth annual meeting took place virtually on April 22 and 23, 2021. The virtual format allowed many more scientists to attend the meeting and we reached over 100 participants from many different countries, while the ENBDC meeting on site usually gathers around 65 participants [1].…”

Section: Introductionmentioning

confidence: 99%

“…This threeday meeting has been hosted every year until now in the charming small town Weggis in Switzerland [1], but the twelfth annual meeting took place virtually on April 22 and 23, 2021. The virtual format allowed many more scientists to attend the meeting and we reached over 100 participants from many different countries, while the ENBDC meeting on site usually gathers around 65 participants [1]. The meeting schedule was rearranged to fit in two full days, with regular breaks, and more relaxed poster sessions in the afternoon.…”

Section: Introductionmentioning

confidence: 99%

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Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

Charifou

Traustadóttir

Bentires‐Alj

et al. 2021

J Mammary Gland Biol Neoplasia

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The twelfth annual workshop of the European Network for Breast Development and Cancer focused on methods in mammary gland biology and breast cancer, was scheduled to take place on March 26–28, 2020, in Weggis, Switzerland. Due to the COVID-19 pandemic, the meeting was rescheduled twice and eventually happened as a virtual meeting on April 22 and 23, 2021. The main topics of the meeting were branching and development of the mammary gland, tumor microenvironment, circulating tumor cells, tumor dormancy and breast cancer metastasis. Novel and unpublished findings related to these topics were presented, with a particular focus on the methods used to obtain them. Virtual poster sessions were a success, with many constructive and fruitful interactions between researchers and covered many areas of mammary gland biology and breast cancer.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

Charifou

Traustadóttir

Bentires‐Alj

et al. 2021

J Mammary Gland Biol Neoplasia

Self Cite

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Editorial: Perspectives in Mammary Gland Development and Breast Cancer Research

Vafaizadeh

Peuhu

Keymeulen

et al. 2020

Front. Cell Dev. Biol.

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Editorial on the Research Topic Perspectives in Mammary Gland Development and Breast Cancer Research Annually, researchers from around the world, who work in the field of mammary gland biology and breast cancer and related areas, have a great opportunity to meet and discuss their work at a conference organized by the European Network of Breast Development and Cancer (ENBDC). These meetings, entitled Annual ENBDC Workshop: Methods in mammary gland biology and breast cancer, are largely methodologically oriented. They enable not only presentation of the latest scientific results, but also dissemination of cutting-edge approaches and forefront technologies that have facilitated these discoveries. The latest meeting took place on the 16th to 18th of May 2019 in Weggis, Switzerland, and presented exciting findings achieved using high resolution 'omics approaches, genetic mouse models, organoids, and state-of-the-art imaging (Vafaizadeh et al., 2019). Here, we present a collection of articles based on or related to the topics of the ENBDC workshop. Breast cancer is the most common cancer in women, annually diagnosed in more than 2.1 million women worldwide and more than 650,000 women worldwide die from this heterogeneous disease every year. To improve treatment strategies, deep understanding of breast cancer and metastasis is required. In their review, Parsons and Francavilla discuss how genomics, transcriptomics, proteomics, and metabolomics datasets, in combination with traditional breast cancer models, provide insights into breast cancer biology and enable discovery of novel therapeutic targets or biomarkers. They also emphasize the importance of transparent data sharing in data repositories to allow further meta-analysis and potential discoveries of previously unnoticed biomarkers or therapeutic targets. Waterhouse et al. further discuss the challenges of targeting driver oncogenes of triple negative breast cancer (TNBC). They suggest that identification of protein-protein interactions of TNBC oncogenes is needed to understand their functions in TNBC and to reveal novel therapeutic targets. They provide a nice overview of current and emerging agents for targeting TNBC oncogenes on cell surface, cytoplasm, and nucleus, including different genetic and epigenetic strategies for targeting transcription factors. Three of the articles are focused on specific signaling pathways in breast cancer. van Schie and van Amerongen highlight the role of aberrant WNT-CTNNB1 signaling in human breast cancer and discuss three major gaps in this field: (i) Incomplete understanding of WNT signaling functions in normal human breast development and physiology, (ii) lack of knowledge of the extent and effect of (epi)genetic changes in the WNT pathway in different breast cancer subtypes, and

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The Eleventh ENBDC Workshop: Advances in Technology Help to Unveil Mechanisms of Mammary Gland Development and Cancerogenesis

Cited by 2 publications

References 36 publications

Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

Twelfth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

Editorial: Perspectives in Mammary Gland Development and Breast Cancer Research

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