The embryonic development of the lateral nasal wall from 8 to 24 weeks

Abstract

This histological study of 20 fetal heads aged between 8 and 24 weeks of gestation demonstrates and describes the embryonic development of the lateral wall of the nose. The three turbinates (inferior, middle, and superior) arise as soft-tissue swellings (preturbinates) by 8 weeks' gestation. A cartilage capsule surrounds the nose at 8 weeks and by 9 weeks, medially directed flanges of cartilage have invaded all three preturbinates. The uncinate process arises from the medial surface of the lateral cartilaginous capsule and is first identifiable by 10 weeks. An "air space" progressively develops from 11 to 12 weeks lateral to the cartilaginous uncinate process and from this space, the embryonic channel to the maxillary sinus develops. The embryonic woven bone of the maxilla can be identified from 9 to 10 weeks and enlarges both absolutely and relatively to the nasal cavity, so that by 13 to 14 weeks, this expanding bone forms the lateral wall of the inferior meatus as the cartilaginous nasal capsule regresses.

Maxillary Sinus Hypoplasia, Embryology, and Radiology

“…In this series of fetuses, anterior ethmoidal sinus development pre¬ cedes the appearance of the MS by up to 4 weeks in contrast to reports elsewhere. 13 The uncinate process is identifiable by 12 (Table 1) RADIOLOGY In this series, the most frequent CT features associated with MS hypoplasia were retraction of the fontanelles of the middle meatus and uncinate process abnormali¬ ties (83%). The sinus wall tended to be thicker with a high canine fossa anteriorly (77%).…”

Illustrated Review of the Embryology and Development of the Facial Region, Part 1: Early Face and Lateral Nasal Cavities

“…By 13-14 weeks, the expanding maxilla now forms the lateral wall of the inferior meatus as the cartilaginous capsule regresses. 9 By the 16th week, the primitive maxillary sinus starts to develop from the inferior margin of the infundibulum. 10 In order to be concise and for future reference for Part 2, the Table summarizes the morphologic changes described in both Parts 1 and 2 of these reviews.…”

Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis

“…A cartilaginous nasal septum continuous with the cartilaginous nasal capsule forms the boundary of the nasal cavity (Bingham et al, 1991). This cartilage structure functions as a strut in the nasal cavity, keeping the nasal airway open to enable optimal respiratory and olfactory function (Badoux, 1966;Moss et al, 1968;Stenstrom and Thilander, 1970).…”