The Emergence of Insect Odorant Receptor-Based Biosensors

Bohbot, Jonathan D.; Vernick, Sefi

doi:10.3390/bios10030026

Cited by 42 publications

(31 citation statements)

References 138 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A remarkable application of insect odorant receptor proteins is their use in the fabrication of biosensors (Bohbot and Vernick 2020 ). Such bioelectric noses utilize the odor-specific OrX proteins imbedded in liposomes (Khadka et al 2019 ) or nanodiscs (Murugathas et al 2019 ) as sensing elements for food screening.…”

Section: Outlook and Applicationmentioning

confidence: 99%

Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors

2021

View full text Add to dashboard Cite

The majority of insect olfactory receptors belong to two distinct protein families, the ionotropic receptors (IRs), which are related to the ionotropic glutamate receptor family, and the odorant receptors (ORs), which evolved from the gustatory receptor family. Both receptor types assemble to heteromeric ligand-gated cation channels composed of odor-specific receptor proteins and co-receptor proteins. We here present in short the current view on evolution, function, and regulation of IRs and ORs. Special attention is given on how their functional properties can meet the environmental and ecological challenges an insect has to face.

show abstract

Section: Outlook and Applicationmentioning

confidence: 99%

Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors

2021

View full text Add to dashboard Cite

show abstract

“…This allows the beetles to communicate on the basis of low pheromone concentrations in complex odor mixtures [38]. At present, it is not possible to use OBPs on sensor surfaces for reliable odor detection under field conditions [49].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Early Bark Beetle Infestation Localization by Drone-Based Monoterpene Detection

Paczkowski

Datta

Irion

et al. 2021

Forests

View full text Add to dashboard Cite

The project PROTECTFOREST deals with improvements in early bark beetle (e.g., Ips typographus and Pityogenes chalcographus) detection to allow for fast and effective response to initial infestation. The removal of trees in the early infestation stage can prohibit bark beetle population gradation and successive timber price decrease. A semiconductor gas sensor array was tested in the lab and attached to a drone under artificial and real-life field conditions. The sensor array was able to differentiate between α-pinene amounts and between different temperatures under lab conditions. In the field, the sensor responded to a strong artificial α-pinene source. The real-life field trial above a spruce forest showed preliminary results, as technical and environmental conditions compromised a proof of principle. Further research will evaluate the detection rate of infested trees for the new proposed sensor concept.

show abstract

“…have demonstrated high sensitivity at low cost [ 13 , 16 , 17 ]. However, most of these sensors face challenges in terms of specificity, dependence on external conditions, and ability to discriminate between analytes, to name a few [ 13 ]. While advances are being made in electronic noses [ 18 , 19 ], biosensors appear to be a promising alternative.…”

Section: Introductionmentioning

confidence: 99%

Market Perspectives and Future Fields of Application of Odor Detection Biosensors within the Biological Transformation—A Systematic Analysis

et al. 2021

View full text Add to dashboard Cite

The technological advantages that biosensors have over conventional technical sensors for odor detection and the role they play in the biological transformation have not yet been comprehensively analyzed. However, this is necessary for assessing their suitability for specific fields of application as well as their improvement and development goals. An overview of biological basics of olfactory systems is given and different odor sensor technologies are described and classified in this paper. Specific market potentials of biosensors for odor detection are identified by applying a tailored methodology that enables the derivation and systematic comparison of both the performance profiles of biosensors as well as the requirement profiles for various application fields. Therefore, the fulfillment of defined requirements is evaluated for biosensors by means of 16 selected technical criteria in order to determine a specific performance profile. Further, a selection of application fields, namely healthcare, food industry, agriculture, cosmetics, safety applications, environmental monitoring for odor detection sensors is derived to compare the importance of the criteria for each of the fields, leading to market-specific requirement profiles. The analysis reveals that the requirement criteria considered to be the most important ones across all application fields are high specificity, high selectivity, high repeat accuracy, high resolution, high accuracy, and high sensitivity. All these criteria, except for the repeat accuracy, can potentially be better met by biosensors than by technical sensors, according to the results obtained. Therefore, biosensor technology in general has a high application potential for all the areas of application under consideration. Health and safety applications especially are considered to have high potential for biosensors due to their correspondence between requirement and performance profiles. Special attention is paid to new areas of application that require multi-sensing capability. Application scenarios for multi-sensing biosensors are therefore derived. Moreover, the role of biosensors within the biological transformation is discussed.

show abstract

The Emergence of Insect Odorant Receptor-Based Biosensors

Cited by 42 publications

References 138 publications

Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors

Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors

Evaluation of Early Bark Beetle Infestation Localization by Drone-Based Monoterpene Detection

Market Perspectives and Future Fields of Application of Odor Detection Biosensors within the Biological Transformation—A Systematic Analysis

Contact Info

Product

Resources

About