The emergence of sulfoxides as efficient ligands in transition metal catalysis

Abstract

Sulfoxides are capable of forming stable complexes with transition metals and there have been many comprehensive studies into their binding properties. However, the use of sulfoxides, particularly chiral sulfoxides, as ligands in transition metal catalysis is rather less well developed. This review aims to describe these catalytic studies and covers new developments that are showing very promising results and that have led to a renewed interest in this field.

Density Functional Computations for Co(I)‐Catalyzed Intermolecular Hydroacylation of Benzaldehydes

“…Transition‐metal‐catalyzed C−H functionalization reactions have been established as a convenient and powerful tool in the organic chemistry and organometallic chemistry . Hydroacylation, the catalytic addition of a formyl C−H bond across an alkene, alkyne, aldehyde, or ketone, represents an ordinary, atom‐efficient, viable, green method to carbonyl compounds.…”

“…Transition-metal-catalyzed CÀ H functionalization reactions have been established as a convenient and powerful tool in the organic chemistry and organometallic chemistry. [1][2][3][4] Hydroacylation, [5][6][7] the catalytic addition of a formyl CÀ H bond across an alkene, alkyne, aldehyde, or ketone, represents an ordinary, atom-efficient, viable, green method to carbonyl compounds. Many transition metals such as cobalt, [8][9][10][11][12] nickel, [13][14] copper, [15][16] ruthenium, [17][18] rhodium, [19][20] palladium, [21] iridium, [22][23] and gold [24] have been reported to catalyze intramolecular or intermolecular hydroacylation.…”

Substituent effect and ligand exchange control the reactivity in ruthenium(II)-catalyzed hydroacylation of isoprenes and aldehydes ‖ A DFT study

“…[1][2][3][4][5][6][7][8][9][10][11] Hydroacylation is one of the most useful C-H bond activation processes, [7][8][9][10][11] and represents an ordinary, green, atom-e±cient synthetic approach. 12 Enormous e®orts have been devoted to develop more convenient and e±cient strategies for catalytic hydroacylation.…”

Self-disproportionation of enantiomers (SDE) of chiral sulfur-containing compounds via achiral chromatography

“…69,71,[74][75][76] Several review articles are devoted to this topic. [77][78][79][80][81][82][83][84] Moreover, sulfoxides are present in many natural products and they play an important role in biology. 85 Moreover, a few sulfoxides have found application in medicinal chemistry.…”