The emerging diagnostic and therapeutic roles of small nucleolar RNAs in lung diseases

Li, Xiaoying; Ali, Khadem; Zhao, Liang; Dua, Kamal; Mao, Yuqiang

doi:10.1016/j.biopha.2023.114519

Cited by 9 publications

(2 citation statements)

References 80 publications

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“…In glioma tumours, overexpressed SNORD47 may serve as an oncogene negatively correlated with the stage of glioma and positively correlated with survival time, while SNORD44 may be protective and significantly down-regulated in glioma. This is similar to the effect of SNORD 76 [68,70].…”

Section: Small Nucleolar Rnassupporting

confidence: 78%

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Non-Coding RNAs in Human Cancer and Other Diseases: Overview of the Diagnostic Potential

Beňačka,

Szabóová,

Guľašová

et al. 2023

IJMS

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Non-coding RNAs (ncRNAs) are abundant single-stranded RNA molecules in human cells, involved in various cellular processes ranging from DNA replication and mRNA translation regulation to genome stability defense. MicroRNAs are multifunctional ncRNA molecules of 18–24 nt in length, involved in gene silencing through base-pair complementary binding to target mRNA transcripts. piwi-interacting RNAs are an animal-specific class of small ncRNAs sized 26–31 nt, responsible for the defense of genome stability via the epigenetic and post-transcriptional silencing of transposable elements. Long non-coding RNAs are ncRNA molecules defined as transcripts of more than 200 nucleotides, their function depending on localization, and varying from the regulation of cell differentiation and development to the regulation of telomere-specific heterochromatin modifications. The current review provides recent data on the several forms of small and long non-coding RNA’s potential to act as diagnostic, prognostic or therapeutic target for various human diseases.

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Section: Small Nucleolar Rnassupporting

confidence: 78%

“…SNORA42 has been proven to be an oncogene in lung cancer. The expression of SNORA65, SNORA7A, and SNORA7B is also increased in NSCLC [60,68]. The expression of SNORD42, SNORD44, SNORA55, SNORD78, SNORD74, and SNORD81 is significantly increased in prostate cancer [69].…”

Section: Small Nucleolar Rnasmentioning

confidence: 95%