The endoscopic appearance of anaphylactoid purpura

Akdamar, K.; Agrawal, Neeti; Varela, P.Y.

doi:10.1016/s0016-5107(73)73878-5

Cited by 10 publications

(5 citation statements)

References 4 publications

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“…Although several reports have recently appeared on endoscopic abnormalities in the gastrointestinal (GI) tract in HSP [1,4,5,8,13,15], the role of endoscopy in the diagnosis and management of this disease remains unclear. The purpose of the present study was to describe the endoscopic findings in children with HSP, including two patients without rash at the time of endoscopy.…”

Section: Introductionmentioning

confidence: 99%

Gastrointestinal endoscopy in Henoch-Schönlein purpura

et al. 1992

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Gastrointestinal (GI) endoscopy was performed in seven patients with Henoch-Schönlein purpura (HSP). In two patients there were no cutaneous lesions at the time of endoscopy, but inflammation of the duodenum, especially of the second part, led to suspicion of the disease. Upper GI endoscopy showed abnormalities in six of seven cases, and sigmoidoscopy in one of four cases. The changes were more marked in the second part of the duodenum rather than in the bulb or the stomach. The endoscopic findings included redness, swelling, petechiae or haemorrhage, erosions and ulceration of the mucosa. Histology of the mucosal biopsy specimens revealed non-specific inflammation with positive staining for IgA in the capillaries, but failed to show vasculitis. Upper GI endoscopy, including study of IgA, can be useful in the diagnosis of HSP. Colonoscopy is less helpful, especially if limited to the sigmoid colon.

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Section: Introductionmentioning

confidence: 99%

Gastrointestinal endoscopy in Henoch-Schönlein purpura

et al. 1992

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“…In both children and adults with HSP, there have been reports of endoscopic changes in the stomach, duodenum, and colon, as previously described (5. 6,[8][9][10][11][12]. Morichau-Beauchant et al (13) have also described severe confluent mucosal involvement of the descending duodenum, similar to the fmdings in patient 2.…”

Section: Discussionmentioning

confidence: 90%

Henoch‐Schönlein Purpura: What does the ‘Rash” Look Like in the Gastrointestinal Mucosa?

1997

Pediatric Dermatology

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Section: Discussionmentioning

confidence: 99%

“…Endoscopic findings of IgAV were first reported in 1973 16 . Akadamar et al 16 showed that the main endoscopic findings of IgAV in the stomach and duodenum were mucosal congestion, redness, petechial, multiple ulcers, nodular change and hematoma-like protrusion. In another study, it thus seems likely that multiple irregular ulcers in the second portion are characteristic of duodenal involvement in IgAV 9 .…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal involvement in patients with vasculitis: IgA vasculitis and eosinophilic granulomatosis with polyangiitis

et al. 2019

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Background and study aims Among vasculitides, IgA vasculitis (IgAV) and eosinophilic granulomatosis with polyangiitis (EGPA) frequently damage the gastrointestinal tract. However, only a few studies have investigated the entire gastrointestinal tract in patients with IgAV or EGPA by endoscopy. The aim of this study was to clarify endoscopic characteristics of patients with IgAV and those with EGPA. Patients and methods Clinicopathological and endoscopic findings were retrospectively compared between 33 patients with IgAV and 19 patients with EGPA. Results Gastrointestinal involvement was observed in 33 patients with IgAV (100 %) and in 8 patients with EPGA (42 %; P = 0.0001). Duodenal involvement was more frequent in patients with IgAV (75.8 %) than in those with EGPA (21.1 %, P = 0.0002). Jejunoileal involvement was frequent in both groups (IgAV 94.4 %; EGPA 77.8 %). Gastric mucosal erythema was more frequent in patients with IgAV (18.2 %) than in those with EGPA (0 %, P = 0.0481). Duodenal mucosal erythema (IgAV 54.6 %; EGPA 21.1 %, P = 0.0227), ulcer (IgAV 33.3 %; EGPA 0 %, P = 0.0041), and hematoma-like protrusion (IgAV 21.1 %; EGPA 0 %, P = 0.039) were more frequently observed in patients with IgAV than in those with EGPA. Conclusions Frequent duodenal involvement, gastric mucosal erythema, and duodenal lesions including erythema, ulcer, and hematoma-like protrusion are characteristic of patients with IgAV. Because jejunoileal involvement was frequent in both groups of patients, small-bowel endoscopies should be performed for diagnosis of small-bowel lesions in patients with IgAV and EGPA.

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The endoscopic appearance of anaphylactoid purpura

Cited by 10 publications

References 4 publications

Gastrointestinal endoscopy in Henoch-Schönlein purpura

Gastrointestinal endoscopy in Henoch-Schönlein purpura

Henoch‐Schönlein Purpura: What does the ‘Rash” Look Like in the Gastrointestinal Mucosa?

Gastrointestinal involvement in patients with vasculitis: IgA vasculitis and eosinophilic granulomatosis with polyangiitis

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