The enigmatic phenotype: Relevant signs and symptoms in schizophrenia

Wijers, F.W.H.M.; Verhoeven, W.M.A.; Tuinier, S.

doi:10.4321/s0213-61632005000400003

Cited by 4 publications

(3 citation statements)

References 127 publications

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“…PPI deficits interacted with strain in animal models and antipsychotic medication in humans (Olivier et al, 2001;Powell and Geyer, 2002;Cilia et al, 2005;Geyer, 2006;Swerdlow et al, 2006;Csomor et al, 2008;Young et al, 2007). Verhoeven and Tunier (2008) discussed the genetic underpinnings of schizophrenia from the perspective of a broad clinical phenotype regarding developmental issues, symptoms and co-morbidity (Verhoeven and Tunier, 2001;Wijers et al, 2005;Cuesta et al, 2007). Verhoeven and Tunier (2008) discussed the genetic underpinnings of schizophrenia from the perspective of a broad clinical phenotype regarding developmental issues, symptoms and co-morbidity (Verhoeven and Tunier, 2001;Wijers et al, 2005;Cuesta et al, 2007).…”

Section: Functionality and Dysfunctionalitymentioning

confidence: 99%

Focusing on symptoms rather than diagnoses in brain dysfunction: Conscious and nonconscious expression in impulsiveness and decision-making

et al. 2008

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Symptoms and syndromes in neuropathology, whether expressed in conscious or nonconscious behaviour, remain imbedded in often complex diagnostic categories. Symptom-based strategies for studying brain disease states are driven by assessments of presenting symptoms, signs, assay results, neuroimages and biomarkers. In the present account, symptom-based strategies are contrasted with existing diagnostic classifications. Topics include brain areas and regional circuitry underlying decision-making and impulsiveness, and motor and learned expressions of explicit and implicit processes. In three self-report studies on young adult and adolescent healthy individuals, it was observed that linear regression analyses between positive and negative affect, self-esteem, four different types of situational motivation: intrinsic, identified regulation, extrinsic regulation and amotivation, and impulsiveness predicted significant associations between impulsiveness with negative affect and lack of motivation (i.e., amotivation) and internal locus of control, on the one hand, and non-impulsiveness with positive affect, self-esteem, and high motivation (i.e., intrinsic motivation and identified regulation), on the other. Although presymptomatic, these cognitive-affective characterizations illustrate individuals' choice behaviour in appraisals of situations, events and proclivities essentially of distal perspective. Neuropathological expressions provide the proximal realities of symptoms and syndromes with underlying dysfunctionality of brain regions, circuits and molecular mechanisms.

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Section: Functionality and Dysfunctionalitymentioning

confidence: 99%

Focusing on symptoms rather than diagnoses in brain dysfunction: Conscious and nonconscious expression in impulsiveness and decision-making

et al. 2008

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“…Schizophrenia is characterized by tremendous heterogeneity in manifestations, course, as well as prognosis (Wijers, Verhoeven & Tuinier, 2005). This heterogeneity brings to the fore an interest in the role of personality and self-esteem in the adaptation process to schizophrenia.…”

Section: Significance Of the Studymentioning

confidence: 99%

Relationship Between Self-Esteem and Personality Traits Among Schizophrenic Patients

Saied

Berma

Hamza

2022

Port Said Scientific Journal of Nursing

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Background: Schizophrenic patients have abnormalities in basic dimensions of personality. Self-esteem might be a driver or resource for the development of personality traits. Aim: This study aimed to evaluate the association between self-esteem and personality traits among schizophrenic patients. Subjects and Method: Design: A descriptive correlational research design was utilized. Setting: This study was carried out at inpatient units in Port Said Psychiatric Health Hospital.Subjects: The study subjects consisted of 104 schizophrenic patients from the above-mentioned setting. Tools: Three tools were used to collect data which were the Rosenberg Self-Esteem Scale, and Big Five Inventory, in addition to personal and Clinical questionnaires. Results: Most of the studied patients had a high score of self-esteem. About half of the studied patients had alow score of extraversion personality. Conclusion: The study concluded that there are highly positive statistically significant relationships between self-esteem and extraversion, agreeableness, conscientiousness, and openness personalities and there is no statistically significant correlation between self-esteem level and neuroticism personality. Recommendation:The study recommended an educational session for schizophrenic patients about specific self-esteem enhancement interventions. An educational session is recommended to psychiatric nurses about preferred approaches to enhance patients' selfesteem and improve their personality from being disordered.

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“…Schizophrenia is characterized by tremendous heterogeneity in manifestation, course, and prognosis (Davidson & McGlashan, 1997;Wijers, Verhoeven & Tuinier, 2005). Moreover, in addition to positive and negative symptoms, which constitute the core of this serious mental illness, people with schizophrenia are also exhibiting elevated levels of depression and suicidality (Birchwood, Iqbal & Upthegrove, 2005) and high prevalence of physical illness (Goldman, 1999).…”

mentioning

confidence: 99%

Role of the Self in Schizophrenia: A Multidimensional Examination of Short-Term Outcomes

Weinberg¹,

Shahar²,

Noyman³

et al. 2012

Psychiatry: Interpersonal and Biological Processes

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The manifestation, course, and prognosis of schizophrenia are extremely variable, raising an interest in the role of personality and self-concept in the illness' outcome. Building on voluminous research attesting to the fragility and instability of the self in schizophrenia, we examined the role of four self-concept aspects--self-esteem level, self-esteem instability, self-concept clarity, and the perception of the self as ill--in schizophrenia-spectrum disorders. Eighty-nine outpatients were assessed at baseline, and five days subsequently, regarding these self-concept aspects, symptoms, stress, and quality of life. Six weeks later, participants were again assessed using the baseline battery. Self-esteem instability predicted a decrease in quality of life over the study period. Self-concept clarity predicted an increase in quality of life and in positive symptoms, particularly under low stress. Depressive symptoms predicted a decrease in self-esteem levels and an increase in the perception of the self as ill. Thus, all four self-concept aspects were shown to be pertinent to the experience of schizophrenia, albeit in different ways. Special attention should be directed to self-concept clarity, which embeds both risk and resilience.

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The enigmatic phenotype: Relevant signs and symptoms in schizophrenia

Cited by 4 publications

References 127 publications

Focusing on symptoms rather than diagnoses in brain dysfunction: Conscious and nonconscious expression in impulsiveness and decision-making

Focusing on symptoms rather than diagnoses in brain dysfunction: Conscious and nonconscious expression in impulsiveness and decision-making

Relationship Between Self-Esteem and Personality Traits Among Schizophrenic Patients

Role of the Self in Schizophrenia: A Multidimensional Examination of Short-Term Outcomes

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