The Epidemiological Characteristics of Epilepsy in the Province of Khyber Pakhtunkhwa, Pakistan

Ullah, Shakir; Ali, Niaz; Khan, Adnan Ahmad; Ali, Saad Emhmed; Nazish, Haleema Rehana

doi:10.3389/fneur.2018.00845

Cited by 19 publications

(13 citation statements)

References 32 publications

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“…In India, alcohol consumption is largely restricted to males, particularly among the lower socioeconomic strata. Similar sex ratios have been reported in previous studies [ 6 - 8 ].…”

Section: Discussionsupporting

confidence: 91%

Evaluation of Acute Symptomatic Seizures and Etiological Factors in a Tertiary Care Hospital From a Developing Country

Vemulapalli¹,

Betdur²,

Harikrishna³

et al. 2022

Cureus

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Introduction: The etiologies of acute symptomatic seizures (ASS) differ across the globe. We aimed to evaluate the etiological spectrum of acute seizures and to observe the pattern of seizure types among study participants.Methodology: We conducted this prospective study from 2016 to 18. We included all patients aged 20 years or older, presenting with ASS. We excluded those with pseudoseizures. We performed appropriate descriptive analyses to describe the demographic details, etiology of ASS, and pattern of ASS.Results: One hundred and thirty-eight patients were enrolled, constituting about 0.8% of total hospital admissions. The mean age at presentation was 44.33 ± 17.73 years. The most common etiologies for ASS were cerebrovascular accidents (CVA -32.6%), neuroinfections (26.8%), metabolic derangements (13%), alcohol withdrawal (10.9%), and intracranial tumors (4.3%). 71% of the patients presented with only a single episode of ASS. The predominant type of seizure was generalized tonic-clonic seizures, seen in 70.2% of all patients, followed by focal with the bilateral tonic-clonic type (15.9%) and focal seizures (10.1%). New-onset seizures presenting as status epilepticus were observed in 3.6%.Discussion: CVA and neuroinfections were the most common causes of ASS in our study, highlighting the need for community awareness of these conditions and the need to seek rapid care. The majority of our patients had only a single episode of seizures, with generalized seizures being the most common type, followed by focal onset seizures.

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“…In India, alcohol consumption is largely restricted to males, particularly among the lower socioeconomic strata. Similar sex ratios have been reported in previous studies [ 6 - 8 ].…”

Section: Discussionsupporting

confidence: 91%

Evaluation of Acute Symptomatic Seizures and Etiological Factors in a Tertiary Care Hospital From a Developing Country

Vemulapalli¹,

Betdur²,

Harikrishna³

et al. 2022

Cureus

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“…In a Pakistani study, Jawaid et al 11 found a mean age of 21.4 ±3.2 years. In studies in SSA and other developing countries, the mean age of epileptic patients ranges from 15 to 20 years, 12,13 unlike in developed countries where epilepsy has a bimodal distribution (i.e. one peak after a few years of birth and the other peak occurs after 65 years).…”

Section: Discussionmentioning

confidence: 99%

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2022

JNSK

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per 1,000 persons) for active epilepsy and 16 per 1,000 persons (95% CI: 12.3-19.7 per 1,000 persons) for lifetime epilepsy, but this estimate was a median figure generated from these studies. These authors found that prevalence was highest in Central Africa at 30.2 per 1,000 people (95% CI: 6.2 to 66.7 per 1,000 persons) and that the prevalence of active epilepsy in rural areas was twice as high as in urban areas. 7 . More than 800,000 people are thought to have epilepsy in the Democratic Republic of the Congo (DRC), where very few epidemiological studies on this condition have been conducted. 8 Etiologies of epilepsy are diverse; they can be infectious, vascular, neoplastic, metabolic, genetic, or degenerative. Head injuries can also cause epilepsy immediately or several years later. Stroke and neurodegenerative diseases may be etiological factors of epilepsy in the elderly. 9 The present study aims to describe socio-demographic characteristics, the type of epileptic seizures, and etiological factors of these seizures in a hospital cohort of epileptic patients followed at the Neuropsychiatric Hospital Center in Goma (in the DRC). Materials and methods Study framework and designThis cross-sectional descriptive study was conducted at the Neuropsychiatric Hospital Center in Goma, North-Kivu province, the eastern DRC (city with about 2 million inhabitants). This hospital is the only hospital in North-Kivu province to provide specialized services in neuropsychiatry and has a bed capacity of 100 patients. Epilepsy prevalence in the community is unknown. Study population and variablesThe present study includes all adults and children admitted for epilepsy. We reviewed the admissions registry from January 1st, 2017 to December 31st, 2021 for patients diagnosed with epilepsy and/or a history of use of anti-epileptic drugs. Following data were collected using a form with a variety of variables and was obtained

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“…Most patients from this study belonged to low socio-economic status. The characteristics associated with poor response to management included low socio-economic status, non-compliance to therapy and generalized onset tonic-clonic seizures [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…Head injuries can also cause seizures either immediately or many years later. In the elderly, stroke and neurodegenerative conditions frequently lead to seizures [4].…”

Section: Introductionmentioning

confidence: 99%

Etiology and Types of Seizures in Patients Presenting to a Tertiary Care Hospital in Karachi: A Cross-Sectional Study

Jawaid¹,

Nisa²,

Umer³

et al. 2020

Cureus

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Introduction Epilepsy is a burdensome disorder for affected individuals and community. There is limited data available on the epidemiological aspects of seizures in Pakistan and further research is necessary. We aimed to fill this gap by studying this information in epilepsy patients presenting to our neurology department. The purpose of this study is to evaluate the causes and types of seizures among the target population. Method This is a cross-sectional study conducted at the Department of Neurology, Dr. Ruth K.M. Pfau Civil Hospital Karachi. In this study we evaluated the causes and types of seizures among patients presenting to our department during the two-year study duration (January 2018-December 2019). Informed consent was taken. Detailed history was taken including features of seizure episodes, age at first seizure, family history and comorbid conditions. Relevant investigations were carried out. The data was compiled to deduce the relevant information using SPSS v20.0. T-test and Chi-square were used for analyzing the data.

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The Epidemiological Characteristics of Epilepsy in the Province of Khyber Pakhtunkhwa, Pakistan

Cited by 19 publications

References 32 publications

Evaluation of Acute Symptomatic Seizures and Etiological Factors in a Tertiary Care Hospital From a Developing Country

Evaluation of Acute Symptomatic Seizures and Etiological Factors in a Tertiary Care Hospital From a Developing Country

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Etiology and Types of Seizures in Patients Presenting to a Tertiary Care Hospital in Karachi: A Cross-Sectional Study

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