The Epidemiology of Congenital Hydrocephalus

Stein, Sherman C.; Feldman, Joseph; Apfel, Stewart; Kohl, Schuyler G.; Casey, Ath

doi:10.1159/000119988

Cited by 9 publications

(10 citation statements)

References 13 publications

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“…The differences between them however make them hard to compare: children with spina bifida were included or not, fetal deaths were taken into consideration or not, studies were population based or hospital based, and there were possible ethnic differences. In the studies since the 1980s, it is agreed that the incidence of congenital and infantile hydrocephalus (20 weeks gestational age-1 year) is 0.12 2.5 per 1000 live and stillbirths [22,46,61,63]. In a group of Swedish children with prenatal onset hydrocephalus [22], toxoplasmosis was an important causative factor; in the peri/postnatal group haemorrhage was the main determinant in preterm babies.…”

Section: Incidence and Frequent Causesmentioning

confidence: 99%

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Congenital hydrocephalus: Nosology and guidelines for clinical approach and genetic counselling

1998

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Section: Incidence and Frequent Causesmentioning

confidence: 99%

“…A high proportion (33%) of the fetal hydrocephalus births are by breech presentation [69]. The fetal death rate is about 24% and neonatal death rate 17% [61]. The presence of additional malformations is a poor prognostic sign.…”

Section: Clinical Approachmentioning

confidence: 99%

Congenital hydrocephalus: Nosology and guidelines for clinical approach and genetic counselling

1998

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“…For the same disorder the prevalence rates in the ICBDMS varies from 2.1 per 10,000 in Spain to 8.5 per 10,000 in Atlanta (7). In a study of more than 233,000 births in Brooklyn, New York, hospitals during the years 1969 to 1979, hydrocephalus occurred at a frequency of 4.93 cases per 10,000 births (15). Data obtained from 1971 to 1987 from 763,364 liveborn and stillborn infants born in maternity hospitals of the U.S. Army showed an incidence of hydrocephalus of 4.8 per 10,000 (22).…”

Section: B) Environmental Factorsmentioning

confidence: 99%

An epidemiologic study of environmental and genetic factors in congenital hydrocephalus

Stoll¹,

Alembik²,

Dott³

et al. 1992

Eur J Epidemiol

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Risk factors were studied in 96 children with congenital hydrocephalus (CH) coming from 118,265 consecutive births of known outcome. Hydrocephalus with neural tube defects, intracranial tumors or secondary to brain atrophy were excluded. The prevalence of CH was 0.81 per thousand. Diagnosis was performed prenatally in 41 cases. Forty-three (44.8%) of the cases had hydrocephalus without other malformations (isolated hydrocephalus), 18 (18.7%) infants had recognized chromosomal or non-chromosomal syndromes and 35 children (36.4%) had multiple malformations. Each case was matched to a control. Weight and length at birth of children with hydrocephalus were less than in the controls (p < 0.001). The weight of the placenta was lower than in the controls (p < 0.05). The pregnancy with a hydrocephalic child was more often complicated by threatened abortion, polyhydramnios and oligohydramnios. The mothers of children with hydrocephalus and multiple malformations had used oral contraceptives during the first trimester of pregnancy more often than the mothers of the controls. No differences appeared between the mothers of children with CH and the controls for the other risk factors studied: parental age, parity, previous pregnancies, previous stillbirths, smoking, diabetes, epilepsy, X-rays, hypertension, fever "flu", medication and occupational exposure. There was an increase of parental consanguinity in the parents of our patients (6.2% v. 1.1%, p < 0.001) and first degree relatives had more non-cerebral malformations than the controls (7.3% v. 3.2%, p < 0.05).

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“…Overall, 78.1% of ICPs performed in newborns involved at least one ventricular ICD-9-CM code. Congenital hydrocephalus occurs at a rate of roughly 60-100 per 100,000 live births in the United States, which would be between 2,000 and 4,000 cases per year [16][17][18] . These patients may require multiple ventricular shunt procedures each, accounting for the relative frequency of these ICPs among newborns.…”

Section: Discussionmentioning

confidence: 99%

Intracranial Procedures and Expected Frequency of Creutzfeldt-Jakob Disease

Abrams

Maddox²,

Schonberger³

et al. 2015

Neuroepidemiology

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Background/Aims: To assess the frequency and characteristics of intracranial procedures (ICPs) performed and the number of US residents living with a history of ICP. These data are used to calculate the expected annual number of sporadic Creutzfeldt-Jakob disease (CJD) cases among US residents with a history of ICP. Methods: The Nationwide Inpatient Sample provided data on the frequency and types of ICPs, and data from the National Center for Health Statistics was used to produce age-adjusted mortality rates. A model was constructed, which estimated long-term survival and sporadic CJD rates among ICP patients based on procedure type and age. Results: There were an estimated 2,070,488 ICPs in the United States from 1998 to 2007, an average of over 200,000 per year. There were an estimated 2,023,726 US residents in 2013 with a history of ICP in the previous 30 years. In 2013, there was expected to be 4.1 sporadic CJD cases (95% CI 1-8) among people with a history of ICP in the past 30 years. Conclusions: The considerable proportion of US residents living with a history of ICP is important information for retrospective assessments of CJD or any other suspected long-term outcome of ICPs.

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The Epidemiology of Congenital Hydrocephalus

Cited by 9 publications

References 13 publications

Congenital hydrocephalus: Nosology and guidelines for clinical approach and genetic counselling

Congenital hydrocephalus: Nosology and guidelines for clinical approach and genetic counselling

An epidemiologic study of environmental and genetic factors in congenital hydrocephalus

Intracranial Procedures and Expected Frequency of Creutzfeldt-Jakob Disease

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