The epidemiology of epilepsy in the Russian Federation

Guekht, Alla; Hauser, W. Allen; Milchakova, Larissa; Churillin, Yury; Shpak, A.A.; Gusev, Eugene

doi:10.1016/j.eplepsyres.2010.09.011

Cited by 60 publications

(30 citation statements)

References 47 publications

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“…Perinatal injuries were frequently associated with epilepsy in our study, as it was in the report from Tunisia [4]. In contrast, in the study of the Russian Federation [11], symptomatic epilepsy was associated with head trauma. In sub-Saharan Africa, the most frequent cause may be related to the occurrence in these areas of neurocysticercosis [12], uncommon in our country.…”

Section: Discussioncontrasting

confidence: 41%

Multicenter Transversal Two-Phase Study to Determine a National Prevalence of Epilepsy in Algeria

et al. 2012

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Background/Aims: The prevalence of epilepsy in Algeria is unknown. The aims of this multicenter transversal study were to determine the national prevalence and clinical characteristics of epilepsy in the Algerian population. Methods: This two-phase study was conducted in 5 circumscriptions and included 8,046 subjects aged over 2 months who attended the randomly selected public and private primary care clinics. In the phase 1 study, a questionnaire was submitted to the sample of patients. In the phase 2 study, all potentially epileptic people were examined by neurologists and a second questionnaire was submitted, eventually assessed by appropriate investigations. Results: Sixty-seven patients were identified as having active epilepsy, giving a crude prevalence ratio of 8.32 per 1,000 (95% CI, 6.34–10.3) and an age-adjusted prevalence ratio of 8.9 per 1,000. The highest age-specific ratio was found in patients aged 10–19 years (16.92 per 1,000). Generalized seizures (68.7%) were more common than partial seizures (29.8%). Perinatal injuries were the major leading putative causes (11.9%). Conclusion: The prevalence of epilepsy of 8.32 determined in this study is relatively high. These results provide new epidemiological data and suggest that epilepsy remains an important public health issue to consider in Algeria.

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Section: Discussioncontrasting

confidence: 41%

Multicenter Transversal Two-Phase Study to Determine a National Prevalence of Epilepsy in Algeria

et al. 2012

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“…Although these studies have identified numerous risk factors associated with epilepsy, the results were highly variable. While stroke and head injury have been implicated as factors for adults from high-income countries (Guekht et al, 2010;Pi et al, 2014), epilepsy was associated with parasitic diseases, perinatal insults and central nervous system (CNS) infections in developing countries (Ogunrin et al, 2013;Asadi-Pooya and Hojabri, 2005;Osakwe et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Consanguinity and epilepsy in Oran, Algeria: A case–control study

et al. 2015

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“…Several international studies have addressed the epidemiology of health care in epilepsy; however, there are a limited number of papers that have addressed the socioeconomic changes in the care provided in the US. 8,15 In their review article, Strzelczyk et al, 17 analyzed the cost of the illness of epilepsy, including indirect expenses to patients with epilepsy, by evaluating 22 studies worldwide. These authors also emphasized the need for studies that evaluate the impact that new antiepileptic treatments have had on the current cost of illness in epilepsy in the US.…”

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confidence: 99%

The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years

Vivas¹,

Baaj²,

Benbadis

et al. 2012

FOC

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Object The aim of this study was to analyze the national health care burden of patients diagnosed with epilepsy in the US and to analyze any changes in the length of stay, mean charges, in-hospital deaths (mortality), and disposition at discharge. Methods A retrospective review of the Nationwide Inpatient Sample (NIS) database for epilepsy admissions was completed for the years from 1993 to 2008. The NIS is maintained by the Agency for Healthcare Research and Quality and represents a 20% random stratified sample of all discharges from nonfederal hospitals within the US. Patients with epilepsy were identified using ICD-9 codes beginning with 345.XX. Approximately 1.1 million hospital admissions were identified over a span of 15 years. Results Over this 15-year period (between 1993 and 2008), the average hospital charge per admission for patients with epilepsy has increased significantly (p < 0.001) from $10,050 to $23,909, an increase of 137.9%. This is in spite of a 33% decrease in average length of stay from 5.9 days to 3.9 days. There has been a decrease in the percentage of in-hospital deaths by 57.9% and an increase in discharge to outside medical institutions. Conclusions The total national charges associated with epilepsy in 2008 were in excess of $2.7 billion (US dollars, normalized). During the studied period, the cost per day for patients rose from $1703.39 to $6130.51. In spite of this drastic increase in health care cost to the patient, medical and surgical treatment for epilepsy has not changed significantly, and epilepsy remains a major source of morbidity.

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The epidemiology of epilepsy in the Russian Federation

Cited by 60 publications

References 47 publications

Multicenter Transversal Two-Phase Study to Determine a National Prevalence of Epilepsy in Algeria

Multicenter Transversal Two-Phase Study to Determine a National Prevalence of Epilepsy in Algeria

Consanguinity and epilepsy in Oran, Algeria: A case–control study

The health care burden of patients with epilepsy in the United States: an analysis of a nationwide database over 15 years

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