The Epidemiology of Functional Gastrointestinal Disorders in Mexico: A Population-Based Study

López‐Colombo, Aurelio; Morgan, Douglas R.; Bravo-González, Dalia; Montiel-Jarquín, Álvaro José; Méndez‐Martínez, Socorro; Schmulson, Max

doi:10.1155/2012/606174

Cited by 86 publications

(72 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, in the study by Jiang et al (4), higher scores on a somatic symptom checklist had a direct association with bloating; this suggests that bloating may partially reflect the process of somatization. In Mexico, 24% of patients with FB suffered from depression based on the Center for Epidemiological Studies Depression Scale (CES-D) (31). In our study, bloating was associated with anxiety, depression, and psychological distress, while FB was only associated with anxiety.…”

Section: Associations With Anxiety Depression and Psychological Dismentioning

confidence: 49%

“…Original Article a prevalence of 13.1% has been reported based on the Rome II criteria, while Tuteja et al (5) reported it to be 7% in US. A prevalence of 21% was also shown in a study on 324 Mexican adults based on the Rome II Modular Questionnaire (7), while another study in the same country reported a prevalence of 10.8% in 2012 (31). Two studies in Iran and Taiwan showed FB prevalences of 1.5% and 2.1% based on the Rome III criteria, respectively (30,32).…”

Section: Prevalence Of Fbmentioning

confidence: 85%

See 1 more Smart Citation

Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Keshteli

Daneshpajouhnejad

Adibi³

2017

Turk J Gastroenterol

View full text Add to dashboard Cite

Background/Aims: Bloating is an unpleasant but common gastrointestinal symptom that is experienced by many people at some stage in their lives. The current survey was conducted to investigate the epidemiology and risk factors of bloating and functional bloating (FB). In addition, we aimed to assess the association between bloating and functional gastrointestinal disorders (FGIDs). Materials and Methods: In this cross-sectional study, the self-administered modified Rome III questionnaire was used to assess gastrointestinal symptoms and FGIDs. Severity of bloating, demographic and anthropometric measurements, physical activity level, psychological distress, and depression and anxiety were also assessed. Results: Among the 4763 participants, 52.9% reported having experienced bloating at least occasionally in the past three months (among which 14.1% had severe or very severe symptoms); 19.7% of subjects were found to have FB. After adjusting for multiple variables, female gender, university degree, obesity, and anxiety were associated with both bloating and FB, while depression and psychological distress were only associated with bloating. The positive predictive value and negative predictive value of bloating for the diagnosis of functional bowel disorder were 92.9% and 80.1%, respectively. Conclusion: Bloating and FB are highly prevalent in the study population. We also identified several demographic, psychological, and lifestyle-related risk factors of bloating in this population. Keywords: Bloating, functional bloating, functional gastrointestinal disorders, Iran, epidemiology Original Article retention, weak anterior wall muscle tone, abnormal gut microflora, inflammation, and altered bowel tonic and phasic motility, none of these has been scientifically proven (3,14). However, studies have shown both increased intestinal gas accumulation and delayed gas transit to be important causes of bloating. Distorted perception and visceral hyperalgesia may also play a role in some patients (2,3,5,14).Physical exercise accelerates gut transit and thus reduces bloating; however, studies on healthy subjects found that physical activity accelerated gas transit but did not affect bloating. The relationship between physical activity and bloating remains unclear (5). Obesity is also an established risk factor for FGIDs; however, data regarding its effects on bloating contain discrepancies (14). Psychological therapies have also been found to be useful in improving bloating and several other FGIDs; however, it remains unclear whether an actual relationship exists between bloating and psychosocial distress (2). Studies have also evaluated the associations of bloating with smoking, marital status, age, and education level (4,5,7); however, data confirming the associations of these variables is limited.The prevalence of bloating, as a symptom, is dramatically higher in subjects who suffer from other FGIDs, notably irritable bowel syndrome (IBS) (4). Studies have shown that more than two thirds of IBS patients may complain ...

show abstract

Section: Associations With Anxiety Depression and Psychological Dismentioning

confidence: 49%

Section: Prevalence Of Fbmentioning

confidence: 85%

Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Keshteli

Daneshpajouhnejad

Adibi³

2017

Turk J Gastroenterol

View full text Add to dashboard Cite

show abstract

“…Moreover, most of these studies diagnosed psychological distress based on medical records or self-reported symptom scales, whereas other studies did not document the diagnosis of reflux with objective testing, rather making the diagnosis of reflux based on the patient's complaint or on medical history [22,23,24,25,26,27]. Thus, the results of these studies could have potential biases related to lack of proper diagnosis of either psychological disorders or reflux problems.…”

Section: Discussionmentioning

confidence: 99%

Studying the Psychological Profile of Patients with Laryngopharyngeal Reflux

Mesallam

Shoeib²,

Farahat³

et al. 2015

Folia Phoniatr Logop

View full text Add to dashboard Cite

Background/Aims: Psychological factors have been claimed to play a role in the predisposition for laryngopharyngeal reflux (LPR) symptoms. The aims of this work were to study the relationship between psychological disorders and LPR and to investigate the effect of potential psychological disorders on patients' self-perception of reflux-related problems. Methods: Forty-two patients with symptoms suggestive of LPR were psychologically evaluated using the Social Readjustment Rating Scale, the Symptom Checklist-90 Revised, the Manifest Anxiety Scale of Taylor, the Minnesota Multiphasic Personality Inventory, and the Zung Self-Rating Depression Scale. Oropharyngeal 24-hour pH monitoring was used to diagnose LPR. LPR-related symptoms were assessed using the reflux symptom index (RSI) and the voice handicap index-10 (VHI-10). Patients were divided into groups based on psychiatric evaluation and pH results. Correlations between psychological profile characteristics and LPR-related parameters were also investigated. Results: No significant difference was found between the positive and negative LPR group for any of the assessed psychological disorders. Also, no significant difference was detected between the positive and negative psychological disorder groups regarding RSI, VHI-10, and pH results. Correlations between psychological profile parameters and LPR-related measures were also nonsignificant. Conclusion: It appears that there is no association between psychological disorders and LPR. The psychological background of the LPR patients had no influence on patients' self-perception of their reflux-related problems.

show abstract

“…All the subjects fulfilling the above criteria answered the Rome II Modular Questionnaire validated in Mexico 19,20 to further categorize them as IBS or controls, regardless of the reason for their medical consultation. IBS was considered when there was abdominal pain or discomfort for at least 12 weeks in the last 12 months that was associated with improvement after defecation and/or associated with a change in defecation frequency and/or associated with a change in stool consistency.…”

Section: Rome II Modular Questionnairementioning

confidence: 99%

Maturation Phenotype of Peripheral Blood Monocyte/Macrophage After Stimulation with Lipopolysaccharides in Irritable Bowel Syndrome

Rodríguez-Fandiño

Hernández-Ruiz

López-Vidal

et al. 2017

J Neurogastroenterol Motil

View full text Add to dashboard Cite

Background/AimsAbnormal immune regulation and increased intestinal permeability augmenting the passage of bacterial molecules that can activate immune cells, such as monocytes/macrophages, have been reported in irritable bowel syndrome (IBS). The aim was to compare the maturation phenotype of monocytes/macrophages (CD14+) from IBS patients and controls in the presence or absence of Escherichia coli lipopolysaccharides (LPS), in vitro. MethodsMononuclear cells were isolated from peripheral blood of 20 Rome II-IBS patients and 19 controls and cultured with or without LPS for 72 hours. The maturation phenotype was examined by flow cytometry as follows: M1-Early (CD11c + CD206 -), M2-Advanced (CD11c -CD206 + CX3CR1 + ); expression of membrane markers was reported as mean fluorescence intensity (MFI). The Mann-Whitney test was used and significance was set at P < 0.05. ResultsIn CD14+ cells, CD11c expression decreased with vs without LPS both in IBS (MFI: 8766.0 ± 730.2 vs 12 920.0 ± 949.2, P < 0.001) and controls (8233.0 ± 613.9 vs 13 750.0 ± 743.3, P < 0.001). M1-Early cells without LPS, showed lower CD11c expression in IBS than controls (MFI: 11 540.0 ± 537.5 vs 13 860.0 ± 893.7, P = 0.040), while both groups showed less CD11c in response to LPS (P < 0.01). Furthermore, the percentage of "Intermediate" (CD11c + CD206 + CX3CR1 + ) cells without LPS, was higher in IBS than controls (IBS = 9.5 ± 1.5% vs C = 4.9 ± 1.4%, P < 0.001). Finally, fractalkine receptor (CX3CR1) expression on M2-Advanced cells was increased when treated with LPS in controls but not in IBS (P < 0.001). ConclusionsThe initial phase of monocyte/macrophage maturation appears to be more advanced in IBS compared to controls. However, the decreased CX3CR1 in patients with IBS, compared to controls, when stimulated with LPS suggests a state of immune activation in IBS.

show abstract

The Epidemiology of Functional Gastrointestinal Disorders in Mexico: A Population-Based Study

Cited by 86 publications

References 36 publications

Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Risk factors of bloating and its association with common gastrointestinal disorders in a sample of Iranian adults

Studying the Psychological Profile of Patients with Laryngopharyngeal Reflux

Maturation Phenotype of Peripheral Blood Monocyte/Macrophage After Stimulation with Lipopolysaccharides in Irritable Bowel Syndrome

Contact Info

Product

Resources

About