The Epidemiology of Osteoporosis

Hadji, Peyman; Klein, S.; Gothe, Holger; Häussler, Bertram; Kless, Thomas; Schmidt, Torsten; Steinle, T.; Verheyen, Frank; Linder, Roland

doi:10.3238/arztebl.2013.0052

Cited by 133 publications

(62 citation statements)

References 14 publications

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“…The prevalence of osteoporosis in Germany in people > 50 years old is estimated to be 5.2–6% in men, 24–39% in women, overall 11.9–14% [32]. In our study, the prevalence was 4% in men and 17% in women aged 50–64 years, rising to 8% in men and 32% in women among 65 to 74-year olds.…”

Section: Discussionsupporting

confidence: 40%

Risk factors for osteoporosis, falls and fractures in hereditary myopathies and sporadic inclusion body myositis — A cross sectional survey

Danckworth

Karabul

Posa

et al. 2014

Molecular Genetics and Metabolism Reports

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BackgroundThe risk of osteoporosis is known in myopathies requiring long-term steroid treatment and Pompe disease, but not in other hereditary myopathies or sporadic inclusion body myositis (sIBM).MethodsRisk factors of osteoporosis, laboratory parameters of bone metabolism, frequency of falls and fractures, walking ability, and pain were surveyed using questionnaires in 89 patients with sIBM and genetically confirmed myopathies facioscapulohumeral muscular dystrophy (FSHD), myotonic dystrophy types 1 and 2 (DM1, DM2), limb girdle muscular dystrophies (LGMD2A, LGMD2B, LGMD2I), MATR3 myopathy, and oculopharyngeal muscular dystrophy (OPMD). Additionally laboratory parameters of bone metabolism were determined.ResultsThe mean age at examination per disease group ranged from 32 years in LGMD2A to 70 years in sIBM. Myopathies with a higher degree of walking impairment had a higher risk of falls (sIBM, LGMD2A, LGMD2B). At the time of examination 3.4% had a history of osteoporosis. The 25-OH D3 level was decreased in 20% of patients (and in 55% of patients with LGMDs), 57% of them were ambulatory. The 25-OH D3 level was significantly lower in patients with myopathies than in other neurological disorders (p < 0.001). 2.7 falls per year per person occurred. Fractures were reported in 6.8% of patients within the last year. They involved frequently the tibia bone. The pain score didn't correlate with either the walking disability (WGMS) score or the 25-OH D3 level.ConclusionThe risk for osteoporosis and reduced 25-OH D3 level seems to be increased in wheelchair-bound patients with myopathy but also in patients with DM1 and autosomal-recessive myopathies.

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Section: Discussionsupporting

confidence: 40%

Risk factors for osteoporosis, falls and fractures in hereditary myopathies and sporadic inclusion body myositis — A cross sectional survey

Danckworth

Karabul

Posa

et al. 2014

Molecular Genetics and Metabolism Reports

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show abstract

“…The prevalence of osteoporosis amongst the over 50 age group is approximately 14 % (women: 24 %; men: 6 %) (Hadji et al 2013).…”

Section: J Femoral Neck Fracturementioning

confidence: 99%

Introduction to the Indications and Procedures

Seidlitz

Kip

2018

White Paper on Joint Replacement

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“…Die Prävalenz der Osteoporose beträgt in der über 50-jährigen Bevölkerung rund 14 % (Frauen: 24 %; Männer: 6 %) (Hadji et al 2013 (Claes et al 2012).…”

Section: Schenkelhalsfrakturunclassified