The Epidemiology of Ruptured Abdominal Aortic Aneurysm (rAAA)

Soden, Peter A.; Schermerhorn, Marc L.

doi:10.1007/978-3-319-23844-9_3

Cited by 3 publications

(2 citation statements)

References 118 publications

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“…Typically, this consists of an older age group with extensive comorbidities and poor baseline health. However, the decision-making in those cases is rather complex and can be affected by many factors, including the surgeon’s decision, the patient’s suitability for endovascular intervention, patient and family choice, and severe hemodynamic instability [ 7 , 14 ]. Reports suggest that the median time from rAAA arrival to death in the nonsurgical group is 435 min, ranging from 15 min to 6 days [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Conservative Treatment of Ruptured Abdominal Aortic Aneurysm

Nasir,

Shoab,

Bani-Hani

2023

Vasc Specialist Int

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Although nonsurgical management of ruptured abdominal aortic aneurysm (rAAA) is still used among a significant number of patients, survival after conservative treatment is extremely rare. We report a case of an 86-year-old female who presented with an rAAA that was confirmed clinically and radiologically via computed tomography angiography. Although the patient was not deemed a candidate for surgery owing to significant comorbidities and poor baseline function, she survived the episode with no surgical intervention. Given the growing aging and frail population, it is vital to explore this further, with the aim of improving both mortality and advanced care planning in the nonsurgical management of rAAA.

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Section: Discussionmentioning

confidence: 99%

Conservative Treatment of Ruptured Abdominal Aortic Aneurysm

Nasir,

Shoab,

Bani-Hani

2023

Vasc Specialist Int

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“…Although AA is rather rare with an incidence of approximately 10 per 100,000 for thoracic aortic aneurysm (ΤΑΑ) ( 3 ) and 55–298 per 100,000 for abdominal aortic aneurysm (AAA) ( 4 ), the burden of the disease is heavy and may be underestimated ( 5 – 7 ). Given the high total mortality estimated at 80–100% for ruptured AA ( 8 , 9 ), the best way to reduce the overall mortality of the disease may be to detect and treat it prior to rupture. In fact, many predictors or predictive models of mortality risk in AA patients have been reported ( 10 – 14 ), but further validation is required.…”

Section: Introductionmentioning

confidence: 99%

Serum anion gap on admission predicts intensive care unit mortality in patients with aortic aneurysm

Chen

et al. 2018

Exp Ther Med

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It has been widely reported that the serum anion gap is significantly associated with mortality in intensive care unit (ICU); however, it remains unknown whether the association is present in aortic aneurysm (AA) patients. The present study aimed to investigate the association between the admission serum anion gap and ICU mortality in AA patients. Data extracted from a publicly accessible clinical database using a modifiable data mining technique were analyzed retrospectively, mainly by employing multivariable logistic regression analysis. The primary study outcome was ICU mortality. A total of 273 patient records were analyzed. The ICU mortality was 8.79% (24/273). The median serum anion gap was significantly higher in non-survivors [17.50 mEq/l, interquartile range (IQR) 15.75–22.50 mEq/l] compared with survivors [13.00 mEq/l, IQR 11.00–15.00 mEq/l, P<0.001]. Multivariate analysis resulted in identification of a clear association between admission serum anion gap and ICU mortality in AA patients [odds ratio (OR) 1.38 per 1 mEq/l increase, 95% confidence interval (CI) 1.08–1.76]. The area under the receiver operating characteristic curve showed an outstanding discrimination ability in predicting ICU mortality (area under curve 0.8513, 95% CI 0.7698–0.9328). In conclusion, admission serum anion gap may serve as a strong predictor of ICU mortality for AA patients.

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