The ERA Registry Annual Report 2019: summary and age comparisons

Abstract

Background Data on renal replacement therapy (RRT) for end-stage renal disease (ESRD) was collected by the European Renal Association (ERA) Registry via national and regional renal registries in Europe and countries bordering the Mediterranean Sea. This paper provides a summary of the 2019 ERA Registry Annual Report, including data from 34 countries and additional age comparisons. Methods Individual patient data for 2019 was provided by 35 registries and aggregated data by 17 registries. Using this data, the incidence and prevalence of RRT, the kidney transplantation activity and the survival probabilities were calculated. Results In 2019, a general population of 680.8 million people was covered by the ERA Registry. Overall, the incidence of RRT was 132 per million population (p.m.p.). Of these patients, 62% were men, 54% were ≥ 65 years of age, 21% had diabetes mellitus as primary renal disease, and 84% had haemodialysis (HD), 11% had peritoneal dialysis (PD) and 5% had pre-emptive kidney transplantation as initial treatment modality. The overall prevalence of RRT on 31 December 2019 was 893 p.m.p., with 58% of patients on HD, 5% on PD, and 37% living with a kidney transplant. The overall kidney transplant rate was 35 p.m.p. and 29% of the kidney grafts were from a living donor. The unadjusted 5-year survival probability was 42.3% for patients commencing dialysis, 86.6% for recipients of deceased donor grafts and 94.4% for recipients of living donor grafts in the period 2010–2014. When comparing age categories, there were substantial differences in the distribution of primary renal disease, treatment modality, kidney donor type, and in the survival probabilities.

The Nephrologist’s Role in the Collaborative Multi-Specialist Network Taking Care of Patients with Diabetes on Maintenance Hemodialysis: An Overview

“…The European Renal Association–European Dialysis and Transplant Association (ERA-EDTA) Report for the year 2019 stated that among the different underlying nephropathies of patients entering into maintenance hemodialysis (HD) in Europe, the incidence of diabetes was 21% [ 1 ].…”

The last pre-pandemic European Renal Association Registry report: age at start of kidney replacement therapy in Europe

“…This issue of CKJ contains the latest edition of the European Renal Association (ERA) Registry Annual Report, corresponding to 2019 [ 1 ]. This is an important document, as it represents the last pre-pandemic annual report and will serve as the baseline that will allow the interpretation of data in the 2020 and subsequent reports.…”

“…Boenink et al . [ 1 ] found substantial differences in the distribution of primary renal disease, treatment modality, kidney donor type and survival probabilities for different age categories among patients in the ERA Registry. These differences may guide the approach of practicing physicians to patient care, since for certain age ranges, often repeated statistics derived from the whole KRT population may not apply but may still guide, e.g.…”

“…However, by clumping them together under ‘miscellaneous’ and separating them from ADPKD, we may be driving them away from the minds of physicians, thus limiting their recognition in clinical practice. Further differences were found in treatment modality, kidney donor type and survival probabilities for different age categories [ 1 ]. Among the latter, it is worth emphasizing the dramatic impact of being on KRT on expected remaining lifetime in younger persons.…”

“…A further finding relates to differences in the median age at the start of KRT and the median age of prevalent patients on KRT [ 1 ]. The median age at the start of KRT ranged from 54.0 years (Ukraine) to 74.4 years (Greece).…”