The Essential Root Oil ofPimpinella major¹

Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites

“…Cybullol (34), a C-8 hydroxyl derivative of geosmin, was isolated during the chemical study of the fungus Cyathus bullery Brodie, a species of gasteromycetous fungi known as bird's nest fungi and widely distributed in nature (Figure 5). The structure was determined by a combination of chemical and physical methods.…”

“…Its absolute configuration was deduced from the circular dichroism spectral of its ketol derivative and by chemical transformation to yield (−)-geosmin [186]. (±)-Cybullol (34) has been synthesized from 6,10-dimethyl-4-octal-3-one, and the transformation of 4,10-dimethyl-4-octal-3-one to (±)-geosmin was described by Ayer et al [147].…”

Bioactive Constituents from TurkishPimpinella Species

“…1, a), and by comparison with the NMR data of phenylpropanoid derivatives previously isolated from Pimpinella species [7] [11]. From these data, the structure of 1 was identified as trans-4-(3-methyloxiranyl-2-yl)phenyl 2-methylbutanoate.…”

Chemical Composition of the Essential Oil from Aerial Parts of Javanian Pimpinella pruatjan Molk. and Its Molecular Phylogeny

“…The genus Pimpinella is known for its essential oils (EOs) [2,[9][10][11]. The oils from Pimpinella species growing across Europe and Asia usually consist of monoterpenes (such as limonene, sabinene, α-pinene, β-pinene, γ-terpinene), norsesquiterpenes (geijerene, pregeijerene), sesquiterpenes 2 of 9 (such as himachalene, δ-elemene, β-bisabolone, caryophyllene, germacrene D), and a high content of phenylpropanoid derivatives with the 2-hydroxy-5-methoxy-1-(E)-propenylbenzene skeleton, known as pseudoisoeugenol [1][2][3][12][13][14]. The presence of pseudoisoeugenol is an important chemosystematic character in the genus of Pimpinella and most likely contributes to the antimicrobial activity of the EOs [2,15].…”