The Establishment oi a Specihc Pathogen Free Cat (Felis catus) Colony

Bleby, John; Lacey, A. L.

doi:10.1111/j.1748-5827.1969.tb04044.x

Cited by 15 publications

(9 citation statements)

References 2 publications

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“…The origin of the SPF cat colony at the laboratory, in 1966, was described by Bleby and Lacey (1969) who reported the methods used to deliver the kittens and their subsequent feeding regimen. When 56 days old they were fed a diet of commercial cat food.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Encephalo‐myelopathy in young cats

Palmer¹,

Cavanagh

1995

J of Small Animal Practice

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Nineteen cats, aged three to 16 months, developed neurological signs including hindleg paralysis, head shaking, nystagmus, defective vision and reduced proprioception. Most of the animals were in cat colonies in research centres and were derived from specific pathogen-free stock. One was referred from veterinary practice. Over 40 per cent of litters could be affected constituting a serious commercial loss. Wallerian degeneration affected long tracts in the spinal cord and variously in the brain stem and cerebral white matter. In seven animals there was loss of Purkinje cells in the cerebellum and in eight there was neuronal loss in the spinal cord. Gliosis accompanied all changes. Although no viral agent was isolated the clinical pattern of the disease and evidence from other cases reported in the literature suggest an infectious cause.

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Section: Clinical Manifestationsmentioning

confidence: 99%

Encephalo‐myelopathy in young cats

Palmer¹,

Cavanagh

1995

J of Small Animal Practice

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“…Many different ways of breeding cats have been described in the literature (Adams & Cox, 1966;La Motte & Short, 1966;Bleby & Lacey, 1969;Robinson & Cox, 1970;Rossbach 1972;Young, 1973;Hurni, 1981;Loveridge, 1984). In 1966, La Motte …”

Section: Discussionmentioning

confidence: 99%

“…Diseases, especially feline enteritis, were responsible for a high level of mortality in both units. For this reason, an SPF colony for cats was established at the UK Laboratory Animal Centre (Bleby & Lacey, 1969). Since then SPF cat breeding units have been established in many places in Europe.…”

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confidence: 99%

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Diet and breeding performance in cats

Sg¹

1986

Lab Anim

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221Summary A conventional cat breeding colony with 70 queens (female cats) was studied during a 4 year period [1979][1980][1981][1982]. During that time the fat content in the diet was increased from 15% to 27% of dry matter. An increase in the number of kittens per litter (from 4,5 to 5,5) and in the annual number of litters per queen (from 1·4 to 2,3) was found. In addition, the mortality decreased from over 20% to 9%. Bodyweight gain under the new diet was such that the males reached 2500 g in 4 months while the females showed this same weight at 5 months of age. Litter size and sex distribution as a function of queen age, litter interval and time of year are presented. It is concluded that husbandry and diet are factors which are of great importance in a cat breeding unit. It is shown that under our conditions it is possible to breed conventional cats with good results.

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“…Towards the end of 1967, an SPF cat colony was also established (Bleby & Lacey, 1969) by hysterectomy and hand rearing.…”

Section: Introduction Of Animalsmentioning

confidence: 99%