The estimated prevalence of no reported dementia-related diagnosis in older Americans living with possible dementia by healthcare utilization

Parker, Kelly; Vincent, Brenda M.; Rhee, Yeong; Choi, Bong-Jin; Robinson‐Lane, Sheria G.; Hamm, Jeremy M.; Klawitter, Lukus; Jurivich, Donald A.; McGrath, Ryan

doi:10.1007/s40520-021-01980-2

Cited by 3 publications

(1 citation statement)

References 34 publications

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“…According Parker et al, 10 the prevalence of no reported dementia-related diagnosis in older individuals is more than 80%. According to Lang et al, 11 the prevalence of undiagnosed dementia is high globally, with a pooled rate of 61.7%.…”

Section: Introductionmentioning

confidence: 99%

Gait variability-based classification of the stages of the cognitive decline using partial least squares-discriminant analysis

Kwak,

Kostic,

Kim

2023

Science Progress

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The purpose of the present study was to examine the differences in gait variability in terms of spatiotemporal, sub-gait cycle, ground reaction force, and the joint profiles of kinematics and kinetics between older individuals with and without risk of potential cognitive impairment, and to derive the crucial features to discriminating the older adults with future risk cognitive decline by using partial least squares-discriminant analysis. A total of 90 community-dwelling older adults aged over 65 years underwent cognitive function assessment and were divided into three groups depending on cognitive assessment score. The participants’ level-walking was analyzed by using three-dimensional instrumented gait analysis. The coefficient of variation was extracted and then comparatively analyzed depending on the stages of the cognitive decline. To identify the most important contributor when differentiating the older adults with a risk of future cognitive decline, partial least squares-discriminant analysis was applied, and the discriminative power of the coefficients confirmed as features of great importance were investigated via the receiver operating characteristic area under the curve. The differences in gait variability were found mainly between the suspected dementia groups and other groups, especially in joint dynamics variables. Through the partial least squares-discriminant analysis, the discriminative features were found as follows: the mid-stance, the moments, and the power in the hip, knee, and ankle joints. In addition, the discrimination model was found to differentiate well between the three groups. The classification accuracy of intact cognition, diminished cognition, and suspected dementia was 0.857, 0.710, and 0.857, respectively. These findings mean that gait variability changes according to continuous cognitive decline, especially in sub-gait cycles and joint biomechanics, and suggest that measures of variation can be used as predictors to identify older individuals with a risk of potential cognitive impairment.

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Section: Introductionmentioning

confidence: 99%

Gait variability-based classification of the stages of the cognitive decline using partial least squares-discriminant analysis

Kwak,

Kostic,

Kim

2023

Science Progress

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Estado cognitivo, emocional y nivel de dependencia en personas adultas y mayores institucionalizadas

Herrero Teijón,

González-Sánchez,

de la Torre

et al. 2024

Revista Española de Geriatría y Gerontología

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Undiagnosed Dementia Is Associated with Poor Physical Function in Older Adults

McGrath

Robinson‐Lane

Klawitter

et al. 2022

JAD

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Background: Older adults with a cognitive impairment, including those not yet diagnosed, may have deficits in their physical function. Objective: We sought to determine the associations of cognitive impairment consistent with dementia (CICD) diagnosis status on handgrip strength, gait speed, and functional disability in older adults. Methods: The analytical sample included 8,383 adults aged ≥65-years without history of stroke, cancers, neurological conditions, or brain damage who participated in at least one-wave of the 2010–2016 waves of the Health and Retirement Study. A handgrip dynamometer measured handgrip strength. Men with handgrip strength <26 kg and women <16 kg were weak. Gait speed was timed across a 2.5-m course and those with slowness had gait speed <0.8 m/s. Participants with difficulty or an inability in completing any basic activities of daily living had a functional disability. The adapted Telephone Interview of Cognitive Status evaluated cognitive function. Persons with scores <7 had a CICD. Healthcare provider dementia-related diagnosis was self-reported. Undiagnosed CICD was defined as no reported dementia-related diagnosis but had CICD, while diagnosed CICD was classified as reporting a dementia-related diagnosis. Covariate-adjusted logistic models were used for the analyses. Results: Persons with undiagnosed CICD had 1.37 (95% confidence interval (CI): 1.04–1.80) greater odds for weakness and 2.02 (CI: 1.39–2.94) greater odds for slow gait speed. Older adults with diagnosed CICD had 2.29 (CI: 1.32–3.97) greater odds for slowness and 1.85 (CI: 1.19–2.90) greater odds for functional disability. Conclusion: Screening for CICD could be recommended when defects in physical function are observed in older adults.

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The estimated prevalence of no reported dementia-related diagnosis in older Americans living with possible dementia by healthcare utilization

Cited by 3 publications

References 34 publications

Gait variability-based classification of the stages of the cognitive decline using partial least squares-discriminant analysis

Gait variability-based classification of the stages of the cognitive decline using partial least squares-discriminant analysis

Estado cognitivo, emocional y nivel de dependencia en personas adultas y mayores institucionalizadas

Undiagnosed Dementia Is Associated with Poor Physical Function in Older Adults

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