The Estimation and Control of Post-Operative Dehydration, With the Aid of Hemoglobin and Plasma Protein Determinations 1

Seaman, B; Ponder, Eric

doi:10.1172/jci101439

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…It was repeatedly discussed, though with the exception of cases of severe burns it received little comment in the literature , Freebody, 1943-4;Vaughan et al, 1946). A similar anaemia may occur after operative intervention which is not preceded by injury (Seaman and Ponder, 1943) and which, as in the cases studied, is not complicated by sepsis or treatment with sulphonamides; the latter often disturbs the picture of trauma. The available data on which to base a description of the anaemia are scanty-in our own series there were only 14 cases, and in none were blood volumes estimated.…”

Section: Anaemia Of Traumamentioning

confidence: 51%

“…For instance, the anaemia occurs after a slight injury such as fracture of the patella when there is no obvious blood loss, and it is progressive. Seaman and Ponder (1943) in a study of anaemia following operative intervention estimated the amount of blood lost by measuring the haemoglobin content of all swabs used and found that the fall in haemoglobin was greater than that accounted for by operative loss.…”

Section: Anaemia Of Traumamentioning

confidence: 99%

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Anaemia Associated with Trauma and Sepsis

Vaughan¹

1948

BMJ

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Section: Anaemia Of Traumamentioning

confidence: 51%

Section: Anaemia Of Traumamentioning

confidence: 99%

Anaemia Associated with Trauma and Sepsis

Vaughan¹

1948

BMJ

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The blood picture and plasma protein level following injury

Vaughn¹,

Thomson²,

Dyson³

1946

J. Pathol.

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OBSERVERS who have followed the blood picture of air-raid and battle casualties have been struck by the fall in haemoglobin level that occurs in the first fortnight after injury. I n the case of burns this fall in hEmoglobin is associated with changes in plasma protein (Vaughan, 1943 ; Taylor et al., 1943 ; Cuthbertson, 1944 ; Anderson and Semeonoff, 1944). The degree of anaemia that may develop appears to be out of proportion to the amount of blood lost at the time of the incident. Apart from burns few accurate and detailed studies have, however, been made of the complete blood picture in such patients. As a first step to an understanding of the stiology of this anaemia and hypoproteinaemia, a study of the peripheral blood picture and protein levels in various types of trauma was planned. Experience has proved that it is not easy to carry out such an investigation in an entirely satisfactory way under war-time conditions. Air-raid casualties are liable to suffer from multiple injuries, often affecting the arms, so that the withdrawal of adequate blood samples is difficult. Patients are constantly transferred without warning to other hospitals and much time is wasted in the pursuit of such patients whvse investigation is not completed. Further, a sudden rush of casualties needing immediate therapeutic help may hold up all investigative work for several days. It has also proved difficult to train the staff in many different hospitals to collect the necessary samples of urine required for pigment analysis. METHODSRed-and white-cell and reticulocyte counts were made by methods already described (Price-Jones, Vaughan and Goddard, 1935). White-cell counts were made on blood withdrawn from the ear; other estimations were made on venous blood, heparin being used as anti-coagulant. When in .certain cases of head injury it was impossible to obtain samples from the ear, venous blood was used. Immediately after the blood had been mixed with heparin a sample was withdrawn into a diluting pipette and mixed with diluting fluid. Differential counts were made on films stained by Jenner's stain. Red-cell fragility in saline was estimated by the method of Dacie and Vaughan (1938).

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Protein deficiency in man

Sahyun

1946

Am. J. Dig. Dis.

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The Estimation and Control of Post-Operative Dehydration, With the Aid of Hemoglobin and Plasma Protein Determinations 1

Cited by 5 publications

References 15 publications

Anaemia Associated with Trauma and Sepsis

Anaemia Associated with Trauma and Sepsis

The blood picture and plasma protein level following injury

Protein deficiency in man

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