Abstract:Hypothyroidism is a common disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. About 12% of the population in the USA will develop substantial thyroid deficiency over their lifetime, mostly as a result of iodine deficiency. The hypothyroidism phenotype also includes individuals that suffer from thyroid development abnormalities (congenital hypothyroidism, CH). Using a large population study, we aimed to identify the functional genes associated with an increase … Show more
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