The European Sero-Epidemiology Network

Osborne, K; Weinberg, Johannes; Miller, Elizbeth

doi:10.2807/esm.02.04.00167-en

Cited by 80 publications

(79 citation statements)

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“…One of the main objectives of the ESEN project was to standardize the methodology for serum bank collection and testing [34]. Each country continued to use their usual ELISA method to detect PT antibody, which have been shown to differ in several aspects resulting in potential problems of comparison [26].…”

Section: Discussionmentioning

confidence: 99%

The seroepidemiology of Bordetella pertussis infection in Western Europe

Pebody¹,

GAY²,

et al. 2004

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SUMMARYHigh titres of pertussis toxin (PT) antibody have been shown to be predictive of recent infection with Bordetella pertussis. The seroprevalence of standardized anti-PT antibody was determined in six Western European countries between 1994 and 1998 and related to historical surveillance and vaccine programme data. Standardized anti-PT titres were calculated for a series of whole-cell and acellular pertussis vaccine trials. For the serological surveys, high-titre sera (>125 units/ml) were distributed throughout all age groups in both high-(>90 %) and low-coverage (<90 %) countries. High-titre sera were more likely in infants in countries using high-titre-producing vaccines in their primary programme (Italy, 11 . 5% ; Western Germany, 13 . 3 % ; France, 4 . 3% ; Eastern Germany, 4 . 0%) compared to other countries (The Netherlands, 0 . 5 %; Finland, 0 %). Recent infection was significantly more likely in adolescents (10-19 years old) and adults in high-coverage countries (Finland, The Netherlands, France, East Germany), whereas infection was more likely in children (3-9 years old) than adolescents in low-coverage (<90% ; Italy, West Germany, United Kingdom) countries. The impact and role of programmatic changes introduced after these surveys aimed at protecting infants from severe disease by accelerating the primary schedule or vaccinating older children and adolescents with booster doses can be evaluated with this approach.

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Section: Discussionmentioning

confidence: 99%

The seroepidemiology of Bordetella pertussis infection in Western Europe

Pebody¹,

GAY²,

et al. 2004

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“…Sera were selected from a serum bank established according to the published guidelines from the European Siro-Epidemiology Network for the surveillance of influenza immunity [7]. Briefly, sera were collected from residual samples taken for biochemical testing from patients attending four hospitals in four regions across Vietnam: Thanh Nhan Hospital in Hanoi (north), Hue Central Hospital in Hue (central coastal), Dak Lak General Hospital in (central highlands) and Gia Dinh Hospital in Ho Chi Minh City (HCMC, south).…”

mentioning

confidence: 99%

Strongyloides stercoralis seroprevalence in Vietnam

et al. 2017

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SUMMARYStrongyloidiasis is a neglected tropical disease caused by the roundworm Strongyloides stercoralis affecting 30-100 million people worldwide. Many Southeast-Asian countries report a high prevalence of S. stercoralis infection, but there are little data from Vietnam. Here, we evaluated the seroprevalence of S. stercoralis related to geography, sex and age in Vietnam through serological testing of anonymized sera. Sera (n = 1710, 1340 adults and 270 children) from an anonymized age-stratified serum bank from four regions in Vietnam between 2012 and 2013 were tested using a commercial Strongyloides ratti immunoglobulin G ELISA. Seroreactivity was found in 29·1% (390/1340) of adults and 5·5% (15/270) of children. Male adults were more frequently seroreactive than females (33·3% vs. 24·9%, P = 0·001). The rural central highlands had the highest seroprevalence (42·4% of adults). Seroreactivity in the other regions was 29·9% (Hue) and 26·0% and 18·2% in the large urban centres of Hanoi and Ho Chi Minh City, respectively. We conclude that seroprevalence of S. stercoralis was high in the Vietnamese adult population, especially in rural areas.

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“…Internationally, a variety of serological methods have been used to collect sera and measure measles antibody levels. The European Sero-Epidemiology Network (ESEN) was established to coordinate and harmonize the serological surveillance of immunity to several vaccine preventable diseases including measles [7]. We present the standardized results of national serological surveys from seven Western European countries performed with comparable designs, providing a unique opportunity not only to compare the serological and epidemiological impact of a variety of measles vaccination schedules and coverage levels, but also to assess progress towards measles control and elimination in Western Europe.…”

Section: Introductionmentioning

confidence: 99%

The seroepidemiology of measles in Western Europe

Melker

Pebody²,

Edmunds³

et al. 2001

Epidemiol. Infect.

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SUMMARYThe European Regional Office of WHO has targeted measles for elimination from the region in 2007. Large national, age and sex stratified serological surveys of measles antibody were conducted in seven Western European countries from 1994-8 as part of the European Seroepidemiology Network. Three patterns were observed in the country-specific measles seroprofiles, ranging from (very) low susceptibility (four countries) to high susceptibility (one country). Susceptibility levels amongst 2-4-year-olds ranged from 2n9 to 29n8 %, in 5-9-yearolds from 2n5 to 25 % and 10-19-year-olds from 2n1 % to 13n9 %. A country's susceptibility profile was highly associated with vaccine coverage for the first dose. First dose coverage ranged from 91 to 97n5 % for low susceptibility countries, 75 to 85 % for intermediate susceptibility countries and 55 % for the high susceptibility country. Only the high susceptibility country still reports epidemic measles. In low susceptibility countries, which have achieved or are very close to measles elimination, the priority will be to maintain high MMR vaccine coverage in all geopolitical units for both vaccine doses. In moderate susceptibility countries

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The European Sero-Epidemiology Network

Abstract: The purpose of serological surveillance is to monitor levels of immunity to particular diseases within a population in order to enhance the quality of information on which public health measures, such as vaccination programmes, are based. Serological surv

Cited by 80 publications

References 0 publications

The seroepidemiology of Bordetella pertussis infection in Western Europe

The seroepidemiology of Bordetella pertussis infection in Western Europe

Strongyloides stercoralis seroprevalence in Vietnam

The seroepidemiology of measles in Western Europe

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