Purpose:To explore the role of stone fragment and ureteric stent in process of intermittent gross hematuria (IGH), discuss the definition of ureteral stent related symptoms (USS) in a setting of lithotripsy and clinical outcomes of IGH. , patients with completed one month follow up after lithotripsy were collected. Based on whether occurrence of IGH, demographics, stent information and clinical outcomes were mainly analyzed.Results: A total of 258 consecutive patients were eventually analyzed, among which 97 patients (37.6%) suffered from IGH. Compared to patients without symptom of IGH, preoperative potassium level (3.89±0.43mmol/L vs. 4.02±0.42mmol/L, p=0.01), initial stone free rate (SFR, 50.52% vs. 68.32%, p=0.007) and potassium citrate application (11.34% vs. 4.55%, p=0.04) were found statistically different in univariate analysis. In multivariate logistic analysis, preoperative potassium level (OR: 0.39, CI: 0.19-0.76, p=0.007), potassium citrate (OR: 2.96, CI: 1.07-8.73, p=0.04), initial SFR (OR: 0.42, CI: 0.24-0.74, p<0.001), and hospital stay (OR: 0.94, CI: 0.89-0.99, p=0.045) were independent risk factors, rather than stent size and stent position. Hemoglobin change, stone area reduction and SFR in one-month follow-up were similar between groups, but more outpatient consultations were found in hematuria group (20 vs. 3, p<0.001), among which 2 patients were readmitted for severe ongoing hematuria.
Conclusions:Stone fragment, rather the size or length of ureteral stent, is the independent risk factors of IGH. Definition of USS is not suitable for IGH after lithotripsy, and a comprehensive inform and enough rest would reduce the unnecessary medical consultations.