The Evaluation of Dentinal Tubule Occlusion by Desensitizing Agents: A Real-time Measurement of Dentinal Fluid Flow Rate and Scanning Electron Microscopy

Kim, S Y; Kim, E J; Kim, D S; Lee, I B

doi:10.2341/11-504-l

Cited by 37 publications

(31 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dentin tubule blocking agents reduce dentin permeability such as potassium oxalate, bioglass, calcium phosphates, arginine-calcium carbonate or dental adhesive materials [13,23]. A reduction in the flow rate reflects the effect of dentinal tubule occlusion was reported by Kim [24]. As such, both Pro-Relief™ and CLP were expected to demonstrate the effect of treating DH to a certain degree based on the results that all the desensitizing agents occluded dentinal tubules.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste

Yang

Lee

et al. 2017

Materials

View full text Add to dashboard Cite

Introduction: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. Methods: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate® Pro-Relief™ paste, CLP paste, and double distilled water (ddH2O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment. One-way ANOVA and post-hoc Tukey’s test were used to determine whether there were any statistically significant differences in dentinal tubule diameter. Results: A significant decrease occurred in the mean tubule diameter for dentin disks treated with CLP paste. A decrease was observed from 3.52 ± 0.83 µm to 2.62 ± 0.42 µm right after treatment, further decreasing to 1.71 ± 0.45 µm after immersion in artificial saliva for 14 days (p < 0.05). Conclusions: The results suggest that the CLP based desensitizing paste has remineralization properties and provides instant and lasting effectiveness in dentinal tubule occlusion.

show abstract

Section: Discussionmentioning

confidence: 99%

In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste

Yang

Lee

et al. 2017

Materials

View full text Add to dashboard Cite

show abstract

“…The methods of relieving dentin sensitivity include inhibition of the liquid within dentinal tubule by physically occluding the dentinal tubule surface; application of stimulation to promote tertiary dentin formation; smear layer formation to occlude dentinal tubules; and induction of occlusion with the use of drugs 13) . Drugs-inducing dentinal tubule occlusion include desensitizing agents and fluoride compounds.…”

Section: Discussionmentioning

confidence: 99%

“…inducing tertiary dentin formation by applying stimulation, inhibiting dentinal fluid movements by physically occluding the dentinal tubule surface 13) , and occluding dentinal tubules through a smear layer formation or the use of hypersensitivity agents 13,14) . Desensitizing agents are widely used in dental hospitals and clinics to occlude dentinal tubules 15,16) .…”

Section: Introductionmentioning

confidence: 99%

Occluding Effect of the Application of Fluoride Compounds and Desensitizers on Dentinal Tubules

Lee¹,

Jeong²,

Ahn³

et al. 2016

Journal of dental hygiene science

View full text Add to dashboard Cite

This study compared and analyzed the occluding effects of fluoride compounds and desensitizers, which are commonly used in dental clinics, on dentinal tubules. This study also evaluated the persistence of the active ingredients over time by performing toothbrushing with an electric toothbrush. Thirty-five molar teeth, which had been extracted within the past 3 months from healthy people without tooth decays, amalgam fillings, or dental crowns, were divided into 4 pieces each. Of these, 135 teeth pieces were used as study specimens. These specimens were divided into a control group, an untreated group, and 5 experimental groups (acidulated fluoride gel, fluoride varnish, Gluma, Super Seal, and SE-Bond). The specimens were then subjected to toothbrushing equivalent to 1 week (140 times), 2 weeks (280 times), and 4 weeks (560 times), and the occluding effects on dentinal tubules in 3 regions of each specimen were examined under a scanning electron microscope. The fluoride varnish treated group showed the highest degree of dentinal tubule occlusion effects during the first, second, and fourth weeks of toothbrushing, with the SE-Bond treated group showing the second highest degree and the Gluma treated group showing the lowest degree. After 4 weeks of toothbrushing, the Gluma treated group and the Super Seal treated group showed the lowest degrees of dentinal tubule occlusion effects. In summary, the fluoride varnish treated group and the SE-Bond treated group displayed higher occlusion effects even after 4 weeks of treatment than did the other experimental groups. Therefore, it is the authors' belief that fluoride varnish and SE-Bond are effective for treating dentinal hyperesthesia.

show abstract

“…Interconnections were covered with nail varnish. The rest of the procedure was as in Kim et al, 2013 [26].…”

Section: Dentin Permeability Evaluationmentioning

confidence: 99%

“…Specimens were connected to a hydraulic pressure device with a liquid flow sensor (ASL 1600, Sensirion, Staefa, Switzerland). A constant hydraulic pressure of 6.9 kPa was applied [26] to simulate physiological pulp pressure [26,27] (Fig 1a).…”

Section: Dentin Permeability Evaluationmentioning

confidence: 99%

Improved reactive nanoparticles to treat dentin hypersensitivity

et al. 2018

View full text Add to dashboard Cite

Erosion from acids provokes dentin hypersensitivity (DH) which presents with intense pain of short duration. Open dentinal tubules and demineralization favor DH. Nanogels based on Ca-nanoparticles and Zn-nanoparticles produced an efficient reduction of fluid flow. Dentinal tubules were filled by precipitation of induced calcium-phosphate deposits. When treating dentin with Zn-nanoparticles, complex modulus values attained at intertubular and peritubular dentin were higher than those obtained after applying Ca-nanoparticles. Zn-nanoparticles are then supposed to fasten active dentin remodeling, with increased maturity and high mechanical properties. Zinc-based nanogels are, therefore, proposed for effective dentin remineralization and tubular occlusion. Further research to finally prove for clinical benefits in patients with dentin hypersensitivity using Zn-doped nanogels is encouraged.

show abstract

The Evaluation of Dentinal Tubule Occlusion by Desensitizing Agents: A Real-time Measurement of Dentinal Fluid Flow Rate and Scanning Electron Microscopy

Cited by 37 publications

References 14 publications

In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste

In Vitro Evaluation of Dentin Tubule Occlusion for Novel Calcium Lactate Phosphate (CLP) Paste

Occluding Effect of the Application of Fluoride Compounds and Desensitizers on Dentinal Tubules

Improved reactive nanoparticles to treat dentin hypersensitivity

Contact Info

Product

Resources

About