Objective:To investigate the relationship between suicide probability and psychological symptoms and coping strategies in hospitalized patients with physical illness.Methods:This cross-sectional study was conducted from April to June 2014 in Bandirma State Hospital, Balikesir, Turkey. The sample of the study consisted of 470 inpatients who met the inclusion criteria and agreed to participate in the study. The data were collected with the Personal Information Form, Suicide Probability Scale, Brief Symptom Inventory and Ways of Coping with Stress Inventory.Results:In the study, 74.7% were at moderate risk for suicide, whereas 20.4% were at high risk for suicide. According to the stepwise multiple linear regression analysis, sub-dimensions of the Ways of Coping with Stress Inventory and Brief Symptom Inventory were the significant predictors of suicide probability.Conclusions:The majority of the patients with physical illness were at risk for suicide probability. Individuals who had psychological symptoms and used maladaptive coping ways obtained significantly higher suicide probability scores.