The evaluation of healing effect of low-level laser treatment following gingivectomy

Abstract

Background: Lasers have been investigated as an alternative or adjunctive tool to conventional procedures commonly used in periodontology. The application of low-level laser therapy (LLLT) in dentistry was proposed to provide minimally invasive and painless treatment as well as increasing the comfort for the patient following surgery. Thus, the purpose of the current study was to evaluate the effect of LLLT on healing following gingivectomy. Methods: Twenty patients with inflammatory gingival enlargement on their maxillary or mandibular anterior region were included in this study. Patients were divided randomly into two groups (test group consist of ten patients) after gingivectomy a diode laser (660 nm) was applied to the wound area immediately post-surgery, 3 and 5 days post-surgery. The control group (ten patients) did not receive laser irradiation. Healing was evaluated clinically using healing score and visual analogue scale (VAS). Results: The laser-treated group had significant improvement regarding the healing score at 5, 7, and 14 days p.s., and significant improvement in visual analogue scale (VAS) score was observed at day 3, 5, and 7 p.s., than the control group. Conclusion: LLLT can be used as an effective adjunctive treatment following gingivectomy procedure to promote healing and decrease patients' discomfort.

Effect of Different Energy Densities of 915 nm Low Power Laser on the Biological Behavior of Human Gingival Fibroblast Cells In Vitro

“…In the present study, no significant changes were detected one day after irradiation compared with the control group, whereas cell viability and viability, on the third day in energy density of 3 J cm −2 and then on the fifth day in energy densities of 2, 3 and 4 J cm −2 were significantly increased compared with the control group. Similarly, in the clinical study of Madi et al ., in the first 24 h after 660 nm laser irradiation with energy density 4 J cm −2 on the wound area after gingivectomy, no significant difference was observed, while a significant improvement in wound healing was found on days 5 and 7 after surgery (20). Although in this clinical study patients were irradiated on the day of surgery and 3 and 5 days after surgery, similar results have been justifiable due to the difference between the tissue absorbance level and the level of cellular absorbance.…”

Modulating the Antioxidant Response for Better Oxidative Stress-Inducing Therapies: How to Take Advantage of Two Sides of the Same Medal?

“…Specifically, low-level laser therapy (LLLT) operating at wavelengths of 600~1000 nm is used for analgesia, helps in tissue regeneration, and decreases inflammation by activating a variety of growth factors, such as vascular endothelial growth factor (VEGF), and transforming growth factor (TGF)-α and −β [224]. Moreover, laser treatments are also used in different medical fields such as dental care [225,226] and gingivectomy procedures [225,227] by promoting the re-epithelialization of cells at a faster rate [228,229]. Like PDT, laser therapy also works through photoreceptor systems in the mitochondria, which further leads to the generation of oxidants (especially ROS) (Table 3) [230].…”

Application and Research Progress of Laser in Periodontal Disease

“…Biostimulation effect of LLLT: The following outcomes have been seen with LLLT on soft and hard tissues: [43][44][45][46] a) Reduction of discomfort and pain. b) Promotion of wound healing.…”