The evaluation of mandibular bone density in chronic periodontitis models

Arina, Yuliana Mahdiyah Da’at; Ferdiansyah, F; Rubianto, Mohamad

doi:10.20473/j.djmkg.v51.i4.p210-215

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…Orthodontic treatment is a way to move a malposition tooth to an appropriate position. Giving external mechanical forces in orthodontic tooth movement influences the remodeling of the periodontal ligament and alveolar bone 1,2 . These external mechanical forces induce neurotransmitters, cytokines, and growth factors, which send signals to pressure-related osteoclasts, causing bone resorption [3][4][5] .…”

Section: Introductionmentioning

confidence: 99%

Expression of TNF-α and TGF-β after the Administration of Cacao Bean Extract on Alveolar Bone

2023

PJMD

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Background: Teeth that are given orthodontic forces can relapse because of excessive resorption on the pressure side. Cocoa bean extract enhances bone apposition during bone remodeling by increasing osteoblast proliferation. This research aimed to ascertain molecular mechanisms of alveolar bone during orthodontic tooth movement applied with cacao bean extract (Theobroma cacao L.) through TNF-α and TGF-β, expressions. Methods: This study utilized an experimental laboratory posttest-only control group design. The NiTi closed coil spring was braced between the right upper first molar and the upper incisor, a strength of 10gf was estimated utilizing a tension gauge to mesially move the upper molars. The total 36 were divided into six groups, Wistar rats were beheaded on days 7 and 14 of treatment. Immunohistochemical staining was utilized to show TNF-α and TGF-β expression. Results were assessed using the one-way ANOVA analysis. Results: The immunohistochemistry findings in osteoclast cells that demonstrate positive results for TGF-β and TNF-α, expression by immunohistochemical staining calculated for each group (control, positive control, treatment). The treatment group (Q14) showed reduced expression (2±0.957) of TNF-α in osteoclast cells. TGF-β, on the other hand, was found with diminished expression in osteoblast cells C-7 and C-14 (3.75±0.816, 3.25±0.957) and increases in the treatment group (Q14) (11.25±0.957). significantly (p=0.000). Conclusion: The administration of cacao bean extract on days 7 and 14 could decrease the expression of TNF-α and increase TGF-β of the treatment group. Therefore, with an increased TNF-α apposition process, relapse after orthodontic treatment can be prevented to accelerate the orthodontic treatment.

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Section: Introductionmentioning

confidence: 99%

Expression of TNF-α and TGF-β after the Administration of Cacao Bean Extract on Alveolar Bone

2023

PJMD

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“…Periodontal disease is an infectious disease caused by bacteria that accumulates in plaque causing the gingiva to become inflamed 1,2 . Factors that affect plaque formation is oral hygiene, diet, composition, and flow rate of the saliva.…”

Section: Introductionmentioning

confidence: 99%

Relationship between Periodontal Health and Adolescent Physical Performance Periodontal Health and Adolescent Physical Performance

Aulia Ramadhani,

Aryo Dwipo Kusumo,

Restu Nurhidayati

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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Background: Oral health problems, including periodontal tissue problems, are important issues that need attention because they can affect a person's quality of life and performance. The prevalence of the periodontal disease in all age groups in Indonesia is 96.58%. Purpose: This study aims to determine the effect of periodontal disease on adolescent physical performance. Method: This research was conducted in an analytic observational manner. The population of this research is adolescents aged 12-14 years in junior high schools in Surabaya, East Java, Indonesia as many as 101 students. Data collection used the Modified Gingival Index (MGI) method and the International Physical Activity Questionnaire (IPAQ). The data analysis used was the ETA correlation test. Result: In the distribution of dental health knowledge, most of the respondents had a low level of knowledge of 88.1%, low physical activity of 44.6%, and good gingival health based on the Modified Gingival Index of 52.5%. Conclusion:There is a significant difference in the level of respondents' Modified Gingival Index based on the respondent's experience of getting dental and oral care and the last time he received dental and oral care.

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Decrease Levels of Matrix Metalloproteinase-8 after Adduction of Erythromycin to Periodontitis patients: A Narrative Review

Kaur Sidhu,

Pudji Rahayu,

Jularso

et al. 2024

RJPT

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Periodontitis is a chronic bacterial infection that affects the gingiva and tooth supporting tissue, causing inflammatory-immune disorders. Matrix metalloproteinase-8 (MMP-8) is a kind of protease that is implicated in the case of periodontitis and can be used in the role of a biomarker. Erythromycin is a type of antibiotic that can be used to treat a variety of bacterial diseases, such as periodontitis. This study aimed to observed that patients with periodontitis have higher levels of matrix metalloproteinase-8 can be reduced with erythromycin. Article references were searched from multiple sources such as google scholar, sciencedirect, NCBI, and Pubmed. The review employed the approach to compare the literature using the same keywords, then came to conclusions. The discovered theories are then summarized in a continuous sequence so that readers can better understand the ideas and advances presented. There were 46 articles from google scholar, sciencedirect, NCBI, and Pubmed that related to diverse literatures. Overall, these results indicate that in periodontitis patients, erythromycin can inhibit MMP 8 production. In periodontitis patients, the medication erythromycin can suppress the synthesis of matrix metalloproteinase-8 (MMP-8) and hence the inflamation.

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The evaluation of mandibular bone density in chronic periodontitis models

Cited by 3 publications

References 16 publications

Expression of TNF-α and TGF-β after the Administration of Cacao Bean Extract on Alveolar Bone

Expression of TNF-α and TGF-β after the Administration of Cacao Bean Extract on Alveolar Bone

Relationship between Periodontal Health and Adolescent Physical Performance Periodontal Health and Adolescent Physical Performance

Decrease Levels of Matrix Metalloproteinase-8 after Adduction of Erythromycin to Periodontitis patients: A Narrative Review

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