The evaluation of metabolic parameters and insulin sensitivity for a more robust diagnosis of the polycystic ovary syndrome

Abstract

Our study highlights the fact that regardless of the diagnostic criteria used, evaluation of the metabolic parameters and insulin sensitivity is important for a correct diagnosis of PCOS and a therapeutic approach.

Metabolic and carbohydrate characteristics of different phenotypes of polycystic ovary syndrome

“…Furthermore, women diagnosed with PCOS according to the AE-PCOS Society criteria had a higher rate of MetS than those with normoandrogenemic PCOS (20.4 vs 9.2%). This significant difference is in line with previous studies (45)(46)(47)(48). The explanation for this quite pronounced difference may be that the key features of MetS comprising abdominal obesity, insulin resistance, and impaired glucose tolerance are present less frequently in normoandrogenemic PCOS (24).…”

Prevalence of Polycystic Ovary Syndrome Phenotypes Using Updated Criteria for Polycystic Ovarian Morphology: An Assessment of Over 100 Consecutive Women Self-reporting Features of Polycystic Ovary Syndrome

“…Applying NIH, Rotterdam, and AE-PCOS Society guidelines, we found a PCOS prevalence of 53%, 70%, and 62%, respectively, consistent with others evaluating PCOS in consecutive patient or unselected populations using older or modified sonographic criteria for PCO. [21][22][23] That the relative prevalence mirrored previous studies likely reflects the use of a consistent cutoff value for OV by all studies-which we recently cocorroborated using new imaging technology 13 -or that use of old criteria for PCO was valid when studies used older sonographic technology. The precise impact of technology is difficult to interpret in this context since studies did not report the age of their equipment.…”

Serum Uric Acid Concentration in Overweight and Obese Women with Polycystic Ovary Syndrome / Nivelul acidului uric la femeile supraponderale și obeze cu sindromul ovarelor polichistice

“…During the past years, it has become evident that alterations in insulin action are frequent in women with PCOS (18)(19)(20)(21)(22)(23)(24). About 60%-70% of PCOS patients present central obesity that is well known to be associated with insulin resistance and increased risk of type 2 diabetes mellitus, hypertension, dyslipidemia, endothelial dysfunction and heart disease (25).…”