The evaluation of occlusal dysfunctional therapy

Nasedkin, John N.

doi:10.1016/0022-3913(80)90036-0

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…As is known from the field of microarrays, data is often incomplete or incompletely annotated and the analyses are hard to reproduce [ 167 ]. For example, four different research groups have reported miRNA profiles for pancreatic cancer, with impressive discrepancies between the results [ 12 , 168 , 169 , 170 ].…”

Section: Mirnas As Reliable Clinical Markers: Advantages and Challmentioning

confidence: 99%

MicroRNA Signatures as Biomarkers and Therapeutic Target for CNS Embryonal Tumors: The Pros and the Cons

Shalaby

Fiaschetti

Baumgärtner

et al. 2014

IJMS

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Embryonal tumors of the central nervous system represent a heterogeneous group of childhood cancers with an unknown pathogenesis; diagnosis, on the basis of histological appearance alone, is controversial and patients’ response to therapy is difficult to predict. They encompass medulloblastoma, atypical teratoid/rhabdoid tumors and a group of primitive neuroectodermal tumors. All are aggressive tumors with the tendency to disseminate throughout the central nervous system. The large amount of genomic and molecular data generated over the last 5–10 years encourages optimism that new molecular targets will soon improve outcomes. Recent neurobiological studies have uncovered the key role of microRNAs (miRNAs) in embryonal tumors biology and their potential use as biomarkers is increasingly being recognized and investigated. However the successful use of microRNAs as reliable biomarkers for the detection and management of pediatric brain tumors represents a substantial challenge. This review debates the importance of miRNAs in the biology of central nervous systemembryonal tumors focusing on medulloblastoma and atypical teratoid/rhabdoid tumors and highlights the advantages as well as the limitations of their prospective application as biomarkers and candidates for molecular therapeutic targets.

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Section: Mirnas As Reliable Clinical Markers: Advantages and Challmentioning

confidence: 99%

MicroRNA Signatures as Biomarkers and Therapeutic Target for CNS Embryonal Tumors: The Pros and the Cons

Shalaby

Fiaschetti

Baumgärtner

et al. 2014

IJMS

View full text Add to dashboard Cite

show abstract

“…The total score of five .•symptoms usually related to PDS or other dental or medieal problems, was rated by a dentist on a two-point scale (yes/no) as shown in Table 1. The ehoiee of these symptoms is adopted from NASEDKIN'S half-minute test (19).…”

Section: Variablesmentioning

confidence: 99%

Relations between TMJ pain dysfunction syndrome (PDS) and some psychologic and biographic variables

Duinkerke¹,

Luteijn²,

Bouman³

et al. 1985

Comm Dent Oral Epid

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A total of 211 persons with a complete natural dentition were examined for signs and symptoms of the TMJ pain dysfunction syndrome. They also answered the questions of the Dutch version of the Hopkins Symptoms Check List (HSCL). Schooling, age and sex were also registered. Signs and symptoms of the TMJ pain dysfunction syndrome proved to be highly correlated to the psychologic and somatic scales of the HSCL with one exception: maximal mouth opening. The total palpation score proved to be a reliable, sensitive, easy and fast predictor for the severity of the TMJ pain dysfunction syndrome.

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Comparison of tests for dysfunction of the stomatognathic system

Duinkerke

Luteijn

Bouman

et al. 1986

Comm Dent Oral Epid

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As part of a validating process, tests and indices for dysfunction of the temporomandibular joints and masticatory muscles were compared and correlated in 211 persons with an almost complete or complete natural dentition. Helkimo's Clinical Dysfunction Index (CDI), the Mandibular Dysfunction Symptoms (MDS) scale from the "Erweiterter Giessener Beschwerdebogen", the Modified Half-Minute (MHM) test and the palpation test for the stomatognathic system (PALP-test) were compared. The PALP-test had the highest internal consistency (coefficient alpha = 0.92) and the highest intercorrelation with the CDI. Furthermore, it was found that the PALP-test and the CDI probably yield the most realistic distribution of persons in the three classes no symptoms, mild to moderate and severe, and also show the highest percentage of absolute correspondence. The MDS-scale and MHM-test scores showed little dispersion and probably indicated too much or too little pathology. The correspondence between the last two measures is mainly due to an overrepresentation of the middle scoring class (mild to moderate indication of dysfunction of the temporomandibular joints and masticatory muscles). In screening procedures this can easily result in an overrepresentation of people with supposed pathology.

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The evaluation of occlusal dysfunctional therapy

Cited by 3 publications

References 4 publications

MicroRNA Signatures as Biomarkers and Therapeutic Target for CNS Embryonal Tumors: The Pros and the Cons

MicroRNA Signatures as Biomarkers and Therapeutic Target for CNS Embryonal Tumors: The Pros and the Cons

Relations between TMJ pain dysfunction syndrome (PDS) and some psychologic and biographic variables

Comparison of tests for dysfunction of the stomatognathic system

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