The evaluation of the retrobulbar orbital fat tissue and optic nerve with strain ratio elastography

Vural, Murat; Acar, Dilek; Toprak, Uğur; Numan, Mehmet; Köz, Özlem Gürbüz; Sayın, Bige; Abat, Gizem Kuşçuoğlu

doi:10.11152/mu.2013.2066.171.muv

Cited by 25 publications

(37 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In some studies, it has been reported that there is a connection between the tissue elasticity and histological features. Elastography is used successfully in prostate, lymph node, breast, thyroid, testis, renal and liver disease examination [12][13][14][15][16]. However, to the best of our knowledge, there has been no work in the previous literature that has investigated the optic nerve with elastography in MS patients.…”

Section: Introductionmentioning

confidence: 81%

“…Histopathological research of the optic nerve in MS showed that prominent axonal loss occurs and the optic nerve cross-sectional area decreases after optic neuritis [6,20,21]. In recent studies significant correlations between the histopathological aspect and the tissue stiffness determined by elastography were established [12,13,22,23].…”

Section: Discussionmentioning

confidence: 99%

“…Also, ocular ultrasound, including Doppler ultrasound is recognized as being a safe, easy to perform method, with no ionizing radiation, that can be used as an imaging method in patients with MS disease and optic neuritis [21,28]. Despite the concerning for the possible biological and side effects of the ocular elastography, there are studies that reported the techniques to be safe and rapid for evaluating the retrobulbar fat tissue and the optic nerve [12,[29][30][31].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of the optic nerve using strain and shear wave elastography in patients with multiple sclerosis and healthy subjects

et al. 2017

View full text Add to dashboard Cite

Aims: Our aim was to evaluate the elasticity features of the optic nerve using strain (SE) and shear wave elastography (SWE) in multiple sclerosis (MS) patients in comparison with healthy subjects. Material and methods: One hundred and seven optic nerves from 54 MS patients and 118 optic nerves from 59 healthy subjects were examined prospectively by SE and SWE. Optic nerves were divided into three types in accordance to the elasticity designs, as follows: type 1 predominantly blue (hardest tissue); type 2 predominantly blue/green (hard tissue); and type 3 predominantly green (intermediate tissue). Quantitative measurements of optic nerve hardness with SWE were analyzed in kilopascals. Results: Elastographic images from healthy volunteers showed mostly type 3 optic nerves (61.9%); type 2 was also found (38.1%), but type 1 was not observed. Elastographic examination of MS patients showed mostly type 2 optic nerves (88%), while some type 1 (4.6%) and type 3 optic nerves (6.5%) were rarely observed. There was a statistically significant difference in terms of elasticity patterns between patients and healthy volunteers (p<0.001). Statistically significant differences were observed between patients and healthy volunteers in the analysis of SWE values (10.381±3.48 kPa and 33.87±11.64 p<0.001). The receiver operating characteristic curve analysis was perfect (0.993; 95% confidence interval [CI]=0.971–0.999), and a cut-off value of 18.3 kPa shear had very high sensitivity and specificity for the patient group. No significant differences were observed between patients with and without previous optic neuritis. Conclusion: SE and SWE examination findings concerning the optic nerve in MS patients demonstrated remarkable differences according to the healthy group.

show abstract

Section: Introductionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of the optic nerve using strain and shear wave elastography in patients with multiple sclerosis and healthy subjects

et al. 2017

View full text Add to dashboard Cite

show abstract

“…SE is observed by applying strain manually by the user and establishing the relative strain in a tissue with comparisons to its surrounding tissue [10,11]. Whereas, SWE simply uses a combination of shear waves, it measure the absolute value of the tissue and delivers tissue elasticity based on force values detected by the machine [12,13].…”

Section: Introductionmentioning

confidence: 99%

Strain Elastography & Tissue Characterisation as a Tool to Differentiate Tumor from Healthy Tissue

Altuwaijri

Javed

2018

JBEMi

View full text Add to dashboard Cite

The purpose of this study was to compare diagnostic values of normal and effected tissues with two techniques using strain elastography and tissues characterization. This study was carried out on a breast phantom containing all human body parameters. Analysis was performed using a lone phantom to correlate a relation between the values of Strain Elastography (SE) and first order texture parameters results. For SE SonixTouch Q+ (Ultrasonix Medical Corporation, 130-4311 Viking Way, Richmond, Canada) device using a linear-array ultrasound probe at a frequency of 10MHz with a gain of 40%. Elastography breast phantom was purchased from CAE healthcare USA, 3600 Edgelake Drive Sarasota FL, USA. For tissue characterization a Region of Interest (ROI) that encompasses both (normal and stiffer) areas were selected. MAZDA software was used to carry out the image analysis (mean and variance) of the tumour and healthy tissue, ROI of 1600 pixels at both regions was selected. An affirmative and resilient outcome was observed between the numerals of normal and tumor tissues, both for SE and first order texture parameters values. After our study we suggest that SE and tissue characterisation via first order texture parameter is a reliable technique to highlight normal and tumor tissue (with respect to same reference, for SE technique only). SE and first order texture parameters (mean and variance) paved way in highlighting the breast tumors fully. It is suggested that SE being more reliable approach in determining the stiffness for breast lesion, as it produces the results with real time imaging. However texture parameter gives an objective assessment of the image with a discriminating feature of the tissue.

show abstract

“…Although grayscale ultrasonography (US) is a noninvasive method that has been used to evaluate the eye structures for many years, elastography is a new technique and is not used as widely for the orbita and orbital structures as for other organs [6,7].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the optic nerve and scleral-choroidal-retinal layer with ultrasound elastography in glaucoma and physiological optic nerve head cupping

et al. 2018

View full text Add to dashboard Cite

Aim: To evaluate the strain ratio of the optic nerve and retina-choroid-sclera (RCS) layers in individuals with physiological optic disc cupping (PC) and glaucoma patients using strain elastography.Material and methods: We evaluated 56 eyes of 56 subjects (20 eyes with glaucoma, 19 eyes with PC, and 17 normal eyes). The strain ratio of orbital fat to optic nerve (SROFON) was calculated as the ratio of the optic nerve to intraconal fat tissue and the strain ratio of orbital fat to retina-choroid-sclera (SROFRCS) was calculated as the ratio of RCS layers to intraconal fat tissue.Results: SROFON was 0.92 in the control group, 1.07 in the PC group and 1.6 in the glaucoma group and a statistically significant difference was present between the three groups (p<0.05). SROFRCS had no statistically significant difference between the three groups.Conclusions: SROFON values could contribute to the differentiation of the patients with glaucoma and PC.

show abstract

The evaluation of the retrobulbar orbital fat tissue and optic nerve with strain ratio elastography

Cited by 25 publications

References 8 publications

Evaluation of the optic nerve using strain and shear wave elastography in patients with multiple sclerosis and healthy subjects

Evaluation of the optic nerve using strain and shear wave elastography in patients with multiple sclerosis and healthy subjects

Strain Elastography & Tissue Characterisation as a Tool to Differentiate Tumor from Healthy Tissue

Evaluation of the optic nerve and scleral-choroidal-retinal layer with ultrasound elastography in glaucoma and physiological optic nerve head cupping

Contact Info

Product

Resources

About