The Evalution of Antibacterial Activity of the (E)-(3-Methoxy-2-Nitroprop-1-Enyl)Benzene Compounds

Abstract

:A simple and convenient synthetic route for the synthesis of (E)-(3-methoxy-2-nitroprop-1-enyl)benzene using Baylis-Hillman chlorides in presence of potassium carbonate and hydroquinone. Baylis-Hillman adducts derived from aldehydes and nitroethylene except the initial report by Baylis and Hillman. This strategy opens new opportunities for the preparation of libraries of a wide variety of new nitro derivatives for biological screening.