The evidence‐based health care debate – 2006. Where are we now?

Miles, Andrew; Polychronis, Andreas; Grey, Joseph E

doi:10.1111/j.1365-2753.2006.00709.x

Cited by 45 publications

(51 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, a number of authors have written criticisms and skeptical reports on different aspects of EBM, ranging from study methodology to its implementation in clinical practice (Sauerland et al 1999, Cohen et al 2004, Miles et al 2006. In this article, we review the history of EBM and discuss the current myths and misconceptions, illustrating them with practical examples.…”

Section: Misconceptions About Practicing Evidence-based Orthopedic Sumentioning

confidence: 99%

“…Current criticisms and limitations of EBM can be grouped into six main arguments (Sauerland et al 1999, Cohen et al 2004, Hannes et al 2005, Miles et al 2006): (1) EBM ignores clinical expertise, (2) EBM is not possible without randomized controlled trials (RCTs), (3) EBM is all about statistics and numbers, (4) the usefulness of applying EBM to individual patients is limited, (5) keeping up to date and finding the evidence is impossible for busy clinicians, and (6) EBM is not evidence-based. Most of the criticisms have their roots in a misunderstanding of the concepts of EBM and are discussed point-by-point below.…”

Section: Misconceptions About Evidence-based Orthopedicmentioning

confidence: 99%

See 1 more Smart Citation

Misconceptions about practicing evidence-based orthopedic surgery

Poolman¹,

Petrisor²,

Marti³

et al. 2007

Acta Orthopaedica

View full text Add to dashboard Cite

Section: Misconceptions About Practicing Evidence-based Orthopedic Sumentioning

confidence: 99%

Section: Misconceptions About Evidence-based Orthopedicmentioning

confidence: 99%

Misconceptions about practicing evidence-based orthopedic surgery

Poolman¹,

Petrisor²,

Marti³

et al. 2007

Acta Orthopaedica

View full text Add to dashboard Cite

“…Here, clinical practice modification and refinement techniques, perhaps via clinical practice guideline development and implementation, may have a role, but their limitations also need to be understood. As noted by Miles and coworkers,21 “clinical practice guidelines remain, when certain conditions are met and their limitations fully understood, useful vehicles for implementing agreed changes to clinical practice and service provision. Certainly, the process of deriving and implementing clinical practice guidelines has developed into a science in its own” (page 243).…”

Section: Discussionmentioning

confidence: 99%

Exploring policy makers' perspectives on a clinical controversy: airway surgery for adult obstructive sleep apnoea

Elshaug

Hiller

Moss

2009

Quality and Safety in Health Care

View full text Add to dashboard Cite

show abstract

“…EBM was codified within the Journal of the American Medical Association nearly two decades ago 3. Yet, the values, philosophical bases, and appropriate research methodologies for EBM are still hotly debated 4–6. In this article, we first review the values and major criticisms of EBM as it is currently conceived.…”

Section: Introductionmentioning

confidence: 99%

Translational systems biology and voice pathophysiology

Li¹,

Abbott

Rosen

et al. 2009

The Laryngoscope

View full text Add to dashboard Cite

Objectives/Hypothesis Personalized medicine has been called upon to tailor healthcare to an individual's needs. Evidence-based medicine (EBM) has advocated using randomized clinical trials with large populations to evaluate treatment effects. However, due to large variations across patients, the results are likely not to apply to an individual patient. We suggest that a complementary, systems biology approach using computational modeling may help tackle biological complexity in order to improve ultimate patient care. The purpose of the article is: 1) to review the pros and cons of EBM, and 2) to discuss the alternative systems biology method and present its utility in clinical voice research. Study Design Tutorial Methods Literature review and discussion. Results We propose that translational systems biology can address many of the limitations of EBM pertinent to voice and other health care domains, and thus complement current health research models. In particular, recent work using mathematical modeling suggests that systems biology has the ability to quantify the highly complex biologic processes underlying voice pathophysiology. Recent data support the premise that this approach can be applied specifically in the case of phonotrauma and surgically induced vocal fold trauma, and may have particular power to address personalized medicine. Conclusions We propose that evidence around vocal health and disease be expanded beyond a population-based method to consider more fully issues of complexity and systems interactions, especially in implementing personalized medicine in voice care and beyond.

show abstract

The evidence‐based health care debate – 2006. Where are we now?

Cited by 45 publications

References 45 publications

Misconceptions about practicing evidence-based orthopedic surgery

Misconceptions about practicing evidence-based orthopedic surgery

Exploring policy makers' perspectives on a clinical controversy: airway surgery for adult obstructive sleep apnoea

Translational systems biology and voice pathophysiology

Contact Info

Product

Resources

About