The evolution of specialist societies into national research networks: a possible solution to the ‘translation problem’

Pandit, J. J.

doi:10.1111/j.1365-2044.2007.05153.x

Cited by 15 publications

(12 citation statements)

References 5 publications

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“…There are no published series examining the safety of TAP block using either technique, and because the incidence of major complications of TAP block is likely to be small, large patient samples will be required to reliably determine the incidence of complications. The need for large surveys, multicentre or even national collaboration has been emphasised [15,16]. Clinical studies that compare ultrasound guided TAP blocks with conventional analgesic techniques including epidural analgesia [17] and intravenous patient controlled analgesia would also be valuable contributions to the literature.…”

Section: Discussionmentioning

confidence: 99%

Spread of injectate after ultrasound‐guided subcostal transversus abdominis plane block: a cadaveric study

Barrington¹,

et al. 2009

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SummaryUltrasound-guided transversus abdominis plane (TAP) block can be performed using a subcostal technique. This technique was simulated using dye injection in cadavers in order to determine segmental nerve involvement and spread of injectate using either single or multiple-injection techniques. Dye most commonly spread to affect T9 and T10 nerves with the single injection technique and T9, T10 and T11 with multiple injections. The median (IQR [range]) spread of dye was 60 (36-63 [32-78]) cm 2 using the single-injection technique and 90 (85-96 [72-136]) cm 2 , in the multiple-injection technique, and this difference was statistically significant (p = 0.003). These results indicate that ultrasound-guided subcostal TAP block will involve nerve roots T9, T10 and T11 and that a multiple-injection technique may block more segmental nerves and increase spread of injectate. The transversus abdominis plane (TAP) block is a regional anaesthesia technique where local anaesthetic is injected into the neurovascular plane between the transversus abdominis and internal oblique muscles. The ventral rami of the segmental thoracolumbar nerves course through the TAP before innervating the anterolateral abdominal wall. The TAP block has been shown to provide postoperative analgesia following abdominal surgery [1][2][3]. These studies have utilised a landmark technique where the injection point into the TAP is through the lumbar triangle in the lateral abdominal wall [4,5]. The TAP block can also be performed with ultrasound imaging to guide injection of local anaesthetic into the neurovascular plane [6][7][8][9]. Real-time imaging of the needle trajectory and injectate spread may improve both safety and block effectiveness. The goal of the TAP block is to anaesthetise several segmental nerves, and recently, we described the extent of nerve involvement using a dye injection study in a cadaver model that simulated an ultrasound-guided TAP block. The probe was placed on the anterolateral abdominal wall between the iliac crest and the costal margin and the needle advanced from an anterior and medial location in a posterolateral direction so that the needle entry point into the TAP was relatively posterior. Using that approach, thoracolumbar nerves, T11, T12 and L1 were the nerves most commonly affected with dye [10].An alternative ultrasound-guided technique is the subcostal TAP block where the probe is placed immediately inferior to the costal margin on the anterior abdominal wall, and an injection made at this location [11]. As a clinical technique, the subcostal ultrasoundguided TAP block may have a different pattern and extent of segmental nerve involvement compared to the posterior technique; hence the primary objective of this anatomical study was to determine the pattern and extent of injectate spread, as measured by segmental nerve involvement with dye and area of dye spread following a simulated ultrasound-guided subcostal TAP block in cadavers. Ultrasound-guided TAP block can be performed using a single-injection or a mul...

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Section: Discussionmentioning

confidence: 99%

Spread of injectate after ultrasound‐guided subcostal transversus abdominis plane block: a cadaveric study

Barrington¹,

et al. 2009

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“…Lack of effective senior faculty research mentoring and a consequent inability of new investigators to successfully earn increasingly competitive US National Institutes of Health (NIH) funds were also identified as key factors in the decline of American anesthesia research [5]. New strategies to revive research were proposed in a number of editorials written by experts in anesthesia research approximately five years ago [5-9]. Whether US research output has increased since in response to or has continued to decrease despite these and other attempts to improve the number or quality of papers produced is unknown.…”

Section: Introductionmentioning

confidence: 99%

Recent trends in publication of basic science and clinical research by United States investigators in anesthesia journals

Pagel

Hudetz

2012

BMC Anesthesiol

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BackgroundUnited States anesthesia research production declined sharply from 1980-2005. Whether this trend has continued despite recent calls to improve output is unknown. We conducted an observational internet analysis to quantify American basic science and clinical anesthesia research output in 14 anesthesia journals with impact factors greater than one at three-year intervals during the past decade.ResultsAmerican investigators published 1,486 (21.7%) of the total of 6,845 research articles identified in anesthesia journals in 2001, 2004, 2007, and 2010. Approximately two-thirds of all US articles were published in Anesthesiology and Anesthesia and Analgesia. There was a significant correlation (r2 = 0.316; P = 0.036) between the number of articles published by American authors in each anesthesia journal and the corresponding journal's impact factor in 2010. Significantly (P < 0.05; Pearson's Chi-square) fewer basic science articles were published in 2007 and 2010 compared with 2001. US clinical research output also declined in 2007 (201; 15.7%) compared with 2001 (266; 19.1%) and 2004, but an increase occurred in 2010 (279; 21.8%, P < 0.05 versus 2007).ConclusionsThe results indicate that US anesthesia research output continued to decrease from 2001 to 2007. An increase in clinical but not basic science research was observed in 2010 compared with 2007, suggesting that a modest recovery in clinical research production may have begun.

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“…A potential solution lies with 'specialist societies' [35], so we turn to the Report's third recommendation. [37,38] helps identify topics suitable for multicenter investigation that would gain the funding support of governmental organizations (such as the Health Technology Assessment division) [36].…”

Section: Methodology Of the Pandit Reportmentioning

confidence: 99%

“…The Pandit Report details how this might be achieved[1 ,30 ,31,35]. The RCA's current Clinical Research Priority Setting Exercise[35,36] (akin to an exercise recently conducted in the USA)…”

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confidence: 99%

Future opportunities and challenges in academic anesthesia in the United Kingdom: a model for maintaining the scientific edge

Pandit

2010

Current Opinion in Anaesthesiology

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The review's main conclusions are: the creation of a central National Institute for Academic Anaesthesia to coordinate and implement academic strategy and funding; engaging with national pathways for the training of future academics; and suggestions for the future role for anesthetic specialist societies in academic strategy. These initiatives can radically transform the research environment in a positive way.

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The evolution of specialist societies into national research networks: a possible solution to the ‘translation problem’

Cited by 15 publications

References 5 publications

Spread of injectate after ultrasound‐guided subcostal transversus abdominis plane block: a cadaveric study

Spread of injectate after ultrasound‐guided subcostal transversus abdominis plane block: a cadaveric study

Recent trends in publication of basic science and clinical research by United States investigators in anesthesia journals

Future opportunities and challenges in academic anesthesia in the United Kingdom: a model for maintaining the scientific edge

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