The Evolution of Stress Conception: From Hans Selye to Modern Achievements

Danylyak, Oleh; Marinets, Sofiya-Anna; Zayachkivska, Оksana

doi:10.25040/ntsh2016.01.027

Cited by 3 publications

(1 citation statement)

References 49 publications

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“…i.e., test/ detect the disease, isolate the infected person, followed up with contact tracing. The more psychological, societal, and physical stressors hit us, the more serious is the resultant distress reaction [31,32].…”

Section: Covid-19: Chaos Panic and Stressmentioning

confidence: 99%

Covid-19: New Disease and Chaos With Panic, Associated With Stress

Szabó

2020

PSSS MS

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COVID-19 (coronavirus disease -2019) caused by SARS-CoV-2 (also known as 2019-nCoV) is a new infectious disease by etiology, but in manifestations it has some similarities with SARS (Sever Acute Respiratory Syndrome) that ravaged several countries of the world around 2003. Coronaviruses are RNA containing microbes that 'hijack' mammalian cells to replicate themselves intracellularly, just to be released in large quantities. SARS-CoV-2 fi rst replicates in the upper respiratory tract, as opposed to SARS-CoV viruses in the 'old' SARS that attack the lower respiratory tree, especially the lungs and cause severe pneumonia. About 80% of COVID-19 patients are mild, some of them are even asymptomatic and only about 10-20% require hospitalization because of pulmonary edema and rapidly developing bronchopneumonia that often leads to multiorgan failure, especially in older patients with chronic comorbidities or immunocompromised system (e.g., obesity, diabetes mellitus, cardiovascular diseases). The overall worldwide mortality is about 1-2%, but some of the genetic variants of the virus caused 4-6% mortality, especially in densely populated areas, like Northern Italy, New York city, Spain. In the most severe cases a 'cytokine storm' (a massive release of cytokines) have been described that aggravate the initial damage in the lungs and heart. Epidemiologically, the true incidence and prevalence of COVID-19, most likely, will never be known because of uneven testing in most of the countries for the viral RNA and/or for the developed IgM and IgG antibodies against the virus. From public health perspectives, the hardest hit areas of the world are those that were not prepared, had a poorly organized or underfunded public health service, and/or did not follow the preventive measures such as social distancing, isolation and frequent hand washing. The poor organization of public health services, especially if associated with initial denial of the rapid spread of the disease lead to chaos, panic and, predictably, sever distress in many people.

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Section: Covid-19: Chaos Panic and Stressmentioning

confidence: 99%

Covid-19: New Disease and Chaos With Panic, Associated With Stress

Szabó

2020

PSSS MS

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Особливості Сприймання Окупованих Міст В Умовах Війни

Хазратова,

Гнатко,

Олійник

2024

PPJ

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Purpose of the article is to empirically determine the peculiarities of perception of occupied cities under the stress of war. Methods. To achieve this goal, the author's questionnaire “Characteristics of Perception of Occupied, Frequently Shelled and Relatively Safe Cities of Ukraine” was used, as well as psychodiagnostic methods aimed at determining: coping strategies by R. Lazarus; stress level by V. Shcherbatykh; anxiety by C. Spielberger. The methods of statistical data processing were correlation and comparative analysis. The group of respondents consisted of 148 citizens of Ukraine (23 men, 125 women) aged 14 to 57 years, who at the time of the study (in 2023) were in 19 different regions of Ukraine and in European countries. Results. The respondents showed a high degree of stress and confrontation coping strategy, as well as its connection with the subjective experience of the value of cities, their emotional significance and “ourness”. The subjective value of the occupied cities is interconnected with the attribution of suffering to their inhabitants, the tragic nature of events in them, and their perceptual value. Gender differences have been identified: women attribute a relatively higher level of “ourness”, emotional significance and value to all Ukrainian cities than men. Women are characterized by a higher level of tragedy in the perception of all the cities assessed; they are more likely to use such coping strategies as distancing, escape, seeking social support, and positive reassessment than men. Differences in stress levels were also found: this level is paradoxically lower among residents of regions closer to the front line than among residents of western regions and people abroad. Residents of the western regions of Ukraine have a lower level of attributed “belongingness” to occupied and de-occupied cities. Conclusions. Experiencing the stress of war and the confrontation coping strategy actualized by it are related to the peculiarities of perception of the occupied cities. They are perceived as tragic, subjectively valuable, and spatially larger. Women ascribe a higher level of “ourness” and emotional significance to all Ukrainian cities and at the same time show a greater variety of coping strategies than men. Residents of the regions close to the front line have lower overall levels of stress and its physical signs than Ukrainian citizens from the western regions and European countries. Residents of the western regions of Ukraine have a lower level of attributed “belongingness” to both occupied and de-occupied cities.

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Modern approaches to the treatment of peptic ulcer disease and prospects for the use of biological therapy

Кошурба

Hladkykh

Chyzh³

2023

Modern Medical Technology

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Digestive diseases are the sixth leading cause of death in the world and accounted for more than 2.5 million deaths in 2019. In Ukraine, mortality from diseases of the digestive system is recorded as one of the highest in the world, and the leading place in the general structure of diseases of the digestive system is occupied by peptic ulcer disease (РUD). The aim of the study. Summarize current information on the etiology and the pathogenesis of РUD and characterize modern approaches to the treatment of patients with РUD and the prospects of biological therapy. Materials and methods. Publications were selected based on the PubMed, Clinical Key Elsevier, Cochrane Library, eBook Business Collection, and Google Scholar databases, which covered information on the etiology, pathogenesis, and approaches to the treatment of РUD. Results. Standard first-line anti-Helicobacter therapy consists of a proton pump inhibitor and two antibiotics, such as clarithromycin and amoxicillin or metronidazole. A promising direction in the treatment of РUD is the use of biological therapy. According to literature sources, the prophylactic use of cryoextract of the placenta in indomethacin gastric lesions has an anti-ulcer effect at the level of 69.1 % and 92.1 % in diclofenac sodium gastric lesions. In addition, the specified cryoextract is capable of leveling the gastrotoxic effect of acetylsalicylic acid, ibuprofen, stress factor and chemical ulcerogens. Conclusions. Today, there is a great need for cell therapy that could be put into practice in clinically relevant volumes. The most promising directions of biological therapy in gastroenterology are considered to be the use of mesenchymal stem cells and agents obtained from the fetoplacental complex.

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The Evolution of Stress Conception: From Hans Selye to Modern Achievements

Abstract: Цього року минає 80 років з дня відкриття Гансом Сельє (1907-1982)

Cited by 3 publications

References 49 publications

Covid-19: New Disease and Chaos With Panic, Associated With Stress

Covid-19: New Disease and Chaos With Panic, Associated With Stress

Особливості Сприймання Окупованих Міст В Умовах Війни

Modern approaches to the treatment of peptic ulcer disease and prospects for the use of biological therapy

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