The evolutionary significance of ancient genome duplications

Peer, Yves Van de; Maere, Steven; Meyer, Axel

doi:10.1038/nrg2600

Cited by 958 publications

(825 citation statements)

References 110 publications

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“…Comparative genome analyses have revealed at least two whole-genome duplication (WGD) events during the early evolution of angiosperms: The first occurred before the monocoteudicot split and the second predated the divergence of major core eudicot lineages (De Bodt et al, 2005;Soltis et al, 2007;Van de Peer et al, 2009a, 2009bProost et al, 2011). Following these WGD events, the genomes of early angiosperms became greatly enlarged with a dramatically increased number of genes.…”

Section: Evolutionary Significance Of the Autoregulatory Loops In Cycmentioning

confidence: 99%

Evolution of Double Positive Autoregulatory Feedback Loops in CYCLOIDEA2 Clade Genes Is Associated with the Origin of Floral Zygomorphy

et al. 2012

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Members of the CYCLOIDEA2 (CYC2) clade of the TEOSINTE BRANCHED1, CYCLOIDEA, and PCF transcription factor genes are widely involved in controlling floral zygomorphy, a key innovation in angiosperm evolution, depending on their persistently asymmetric expression in the corresponding floral domains. However, it is unclear how this asymmetric expression is maintained throughout floral development. Selecting Primulina heterotricha as a model, we examined the expression and function of two CYC2 genes, CYC1C and CYC1D. We analyzed the role of their promoters in protein-DNA interactions and transcription activation using electrophoresis mobility shift assays, chromatin immunoprecipitation, and transient gene expression assays. We find that CYC1C and CYC1D positively autoregulate themselves and cross-regulate each other. Our results reveal a double positive autoregulatory feedback loop, evolved for a pair of CYC2 genes to maintain their expression in developing flowers. Further comparative genome analyses, together with the available expression and function data of CYC2 genes in the core eudicots, suggest that this mechanism might have led to the independent origins of floral zygomorphy, which are associated with plant-insect coevolution and the adaptive radiation of angiosperms.

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Section: Evolutionary Significance Of the Autoregulatory Loops In Cycmentioning

confidence: 99%

Evolution of Double Positive Autoregulatory Feedback Loops in CYCLOIDEA2 Clade Genes Is Associated with the Origin of Floral Zygomorphy

et al. 2012

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“…2014) and other eukaryotic taxa (Van de Peer et al. 2009). Increased recognition of the importance of polyploidy has inspired research highlighting the likelihood that ploidy elevation will often confer major phenotypic (reviewed in Ramsey and Ramsey 2014; Frawley and Orr‐Weaver 2015; e.g ., Neiman et al.…”

Section: Introductionmentioning

confidence: 99%

Effects of polyploidy and reproductive mode on life history trait expression

Larkin

Tucci

Neiman

2016

Ecology and Evolution

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Ploidy elevation is increasingly recognized as a common and important source of genomic variation. Even so, the consequences and biological significance of polyploidy remain unclear, especially in animals. Here, our goal was to identify potential life history costs and benefits of polyploidy by conducting a large multiyear common garden experiment in Potamopyrgus antipodarum, a New Zealand freshwater snail that is a model system for the study of ploidy variation, sexual reproduction, host–parasite coevolution, and invasion ecology. Sexual diploid and asexual triploid and tetraploid P. antipodarum frequently coexist, allowing for powerful direct comparisons across ploidy levels and reproductive modes. Asexual reproduction and polyploidy are very often associated in animals, allowing us to also use these comparisons to address the maintenance of sex, itself one of the most important unresolved questions in evolutionary biology. Our study revealed that sexual diploid P. antipodarum grow and mature substantially more slowly than their asexual polyploid counterparts. We detected a strong negative correlation between the rate of growth and age at reproductive maturity, suggesting that the relatively early maturation of asexual polyploid P. antipodarum is driven by relatively rapid growth. The absence of evidence for life history differences between triploid and tetraploid asexuals indicates that ploidy elevation is unlikely to underlie the differences in trait values that we detected between sexual and asexual snails. Finally, we found that sexual P. antipodarum did not experience discernable phenotypic variance‐related benefits of sex and were more likely to die before achieving reproductive maturity than the asexuals. Taken together, these results suggest that under benign conditions, polyploidy does not impose obvious life history costs in P. antipodarum and that sexual P. antipodarum persist despite substantial life history disadvantages relative to their asexual counterparts.

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“…The common ancestor of all vertebrates is believed to have experienced two rounds (2R) of whole genome duplication (WGD) events about 500-600 million years ago (Mya) (Dehal and Boore, 2005;Ohno, 1970;Van de Peer et al, 2009), and all teleosts are hypothesized to have experienced another ''fish-specific'' (3R) WGD event at approximately 320-350 million Mya (Froschauer et al, 2006;Vandepoele et al, 2004). More recently, polyploidy has independently occurred in some groups of plants and animals.…”

Section: Introductionmentioning

confidence: 99%

Evolutionary history of two divergent Dmrt1 genes reveals two rounds of polyploidy origins in gibel carp

Zhang

et al. 2014

Molecular Phylogenetics and Evolution

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The evolutionary significance of ancient genome duplications

Cited by 958 publications

References 110 publications

Evolution of Double Positive Autoregulatory Feedback Loops in CYCLOIDEA2 Clade Genes Is Associated with the Origin of Floral Zygomorphy

Evolution of Double Positive Autoregulatory Feedback Loops in CYCLOIDEA2 Clade Genes Is Associated with the Origin of Floral Zygomorphy

Effects of polyploidy and reproductive mode on life history trait expression

Evolutionary history of two divergent Dmrt1 genes reveals two rounds of polyploidy origins in gibel carp

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