Objectives. Pharmacy practice is changing in response to several clarion reports published by the Institute of Medicine (IOM) documenting preventable medication errors. This paper seeks to assess the current curricula of US colleges of pharmacy to determine the readiness of new pharmacist graduates to do the pharmacy informatics work necessary to implement a safer, more information-rich medication use system. Methods. Data were collected from course titles and descriptions published on the public Internet web sites of the 89 US colleges of pharmacy recognized as regular institutional members of the American Association of Colleges of Pharmacy (AACP). Results. Of the 88 colleges of pharmacy included, 73 (83%) maintained updated curricula on their web sites. Of the 73 pharmacy curricula studied, only 24 (33%) included courses in pharmacy informatics. Conclusions. In the United States, colleges of pharmacy are formally training only a small portion of their pharmacy students in pharmacy informatics while informatics knowledge is desperately needed to improve medication use practices.