Abstract:Objective: To analyze the correlation between Physiological Cost Index and the 6 Minute Walk Test Parameters and demographics. Participants: Convenience samples of 24 healthy females, age between 25 to 50 years. Intervention: PCI, was calculatedafter measuring the resting vitals, where subject walked at self-selected speed, wearing an ambulatory heart rate meter. For six minute walk test, the subject was asked to walk for six minutes so as to cover maximal distance possible, which was measured, along with posttest vitals to arrive at values of distance covered, VO2max, change in HR, and SBP. correlation between the studied variables and PCI was found to be moderately positively correlated with weight, height, BMI, 6MWD, increase in heart rate post exercise. There was a mild negative correlation between PCI and age, as well as change in SBP. However,VO2 max did not correlate with PCI values. Conclusion: Physiological cost of walking in normal Indian females is directlyassociated with the weight, BMI, 6MWD, increase in heart rate post exercise of the individual. However, the inverse relation between SBP and PCI, and no correlation with VO2 max needs to be investigated further.