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Введение. Для лечения варикозных трофических язв предлагаются способы, основанные на местном воздействии на язву. Применение для местного лечения варикозных трофических язв гипохлорита натрия в доступной нам литературе освещается мало, а сравнения его эффективности с другими лекарственными препаратами при данной патологии – не нашлось.Цель. Показать эффективность гипохлорита натрия при местном лечении варикозных трофических язв и сравнить эффективность гипохлорита натрия с мазями на водорастворимой основе.Материалы и методы. Проведен анализ лечения 83 пациентов с варикозными язвами более 5 см2. Изучено бактерицидное действие гипохлорита натрия на микроорганизмы, выделенные из трофических язв. Проведено сравнение эффективности гипохлорита натрия и мазей на водорастворимой основе при местном лечении варикозных трофических язв.Результаты. Грамотрицательные микроорганизмы выделяются из варикозных язв в 56,8% случаев, грамположительные – в 43,2%. Гипохлорит натрия обладает хорошей антимикробной активностью в отношении как аэробной, так и анаэробной неклостридиальной микрофлоры, при концентрации 0,3 мг/мл в течение 15 мин. они не давали роста. Очищение раневой поверхности варикозных язв при применении гипохлорита натрия происходило быстрее, чем при применении мазей на водорастворимой основе, что составило 28±3 дня при применении гипохлорита натрия и 35±6 дней при применении мазей на водорастворимой основе (Р<0,05).Выводы. Гипохлорит натрия оказывает бактерицидное действие в отношении широкого спектра аэробных и анаэробных микроорганизмов. Использование гипохлорита натрия в 1-й фазе раневого процесса позволяет сократить сроки очищения раневых поверхностей и сроки лечения пациентов с данной патологией в стационаре. Introduction. For varicose trophic ulcers treatment, methods based on local exposure of the ulcer are proposed. The use of sodium hypochlorite in local treatment of variceal trophic ulcers is poorly covered in the available literature, and no comparison of its effectiveness with other medical products in this pathology has been found.Purpose. To demonstrate the effectiveness of sodium hypochlorite in local treatment of varicose trophic ulcers and to compare the effectiveness of sodium hypochlorite with water-soluble ointments.Materials and methods. The treatment of 83 patients with varicose ulcers larger than 5 cm2 was analyzed. The bactericidal effect of sodium hypochlorite on microorganisms isolated from trophic ulcers was studied. A comparison was made of the effectiveness of sodium hypochlorite and water-soluble ointments in the local treatment of varicose trophic ulcers.Results. According to the results of the study, it was found that gram-negative microorganisms are isolated from varicose ulcers in 56.8%, and gram-positive in 43.2%. Sodium hypochlorite has good antimicrobial activity against both aerobic and anaerobic non-clostridial microflora; in concentration of 0.3 mg/ml for 15 minutes they didn’t grow. Purification of the wound surface of varicose ulcers with sodium hypochlorite was faster than with water-soluble ointments, namely, 28±6 days with sodium hypochlorite and 35±3 days with water-soluble ointments (P<0.05).Conclusions. Sodium hypochlorite exhibits a bactericidal effect against a wide range of aerobic and anaerobic microorganisms. The use of sodium hypochlorite in the 1st phase of the wound process allows reducing the time for wound surfaces cleaning as well as the time for treating patients with this pathology in a hospital.
Введение. Для лечения варикозных трофических язв предлагаются способы, основанные на местном воздействии на язву. Применение для местного лечения варикозных трофических язв гипохлорита натрия в доступной нам литературе освещается мало, а сравнения его эффективности с другими лекарственными препаратами при данной патологии – не нашлось.Цель. Показать эффективность гипохлорита натрия при местном лечении варикозных трофических язв и сравнить эффективность гипохлорита натрия с мазями на водорастворимой основе.Материалы и методы. Проведен анализ лечения 83 пациентов с варикозными язвами более 5 см2. Изучено бактерицидное действие гипохлорита натрия на микроорганизмы, выделенные из трофических язв. Проведено сравнение эффективности гипохлорита натрия и мазей на водорастворимой основе при местном лечении варикозных трофических язв.Результаты. Грамотрицательные микроорганизмы выделяются из варикозных язв в 56,8% случаев, грамположительные – в 43,2%. Гипохлорит натрия обладает хорошей антимикробной активностью в отношении как аэробной, так и анаэробной неклостридиальной микрофлоры, при концентрации 0,3 мг/мл в течение 15 мин. они не давали роста. Очищение раневой поверхности варикозных язв при применении гипохлорита натрия происходило быстрее, чем при применении мазей на водорастворимой основе, что составило 28±3 дня при применении гипохлорита натрия и 35±6 дней при применении мазей на водорастворимой основе (Р<0,05).Выводы. Гипохлорит натрия оказывает бактерицидное действие в отношении широкого спектра аэробных и анаэробных микроорганизмов. Использование гипохлорита натрия в 1-й фазе раневого процесса позволяет сократить сроки очищения раневых поверхностей и сроки лечения пациентов с данной патологией в стационаре. Introduction. For varicose trophic ulcers treatment, methods based on local exposure of the ulcer are proposed. The use of sodium hypochlorite in local treatment of variceal trophic ulcers is poorly covered in the available literature, and no comparison of its effectiveness with other medical products in this pathology has been found.Purpose. To demonstrate the effectiveness of sodium hypochlorite in local treatment of varicose trophic ulcers and to compare the effectiveness of sodium hypochlorite with water-soluble ointments.Materials and methods. The treatment of 83 patients with varicose ulcers larger than 5 cm2 was analyzed. The bactericidal effect of sodium hypochlorite on microorganisms isolated from trophic ulcers was studied. A comparison was made of the effectiveness of sodium hypochlorite and water-soluble ointments in the local treatment of varicose trophic ulcers.Results. According to the results of the study, it was found that gram-negative microorganisms are isolated from varicose ulcers in 56.8%, and gram-positive in 43.2%. Sodium hypochlorite has good antimicrobial activity against both aerobic and anaerobic non-clostridial microflora; in concentration of 0.3 mg/ml for 15 minutes they didn’t grow. Purification of the wound surface of varicose ulcers with sodium hypochlorite was faster than with water-soluble ointments, namely, 28±6 days with sodium hypochlorite and 35±3 days with water-soluble ointments (P<0.05).Conclusions. Sodium hypochlorite exhibits a bactericidal effect against a wide range of aerobic and anaerobic microorganisms. The use of sodium hypochlorite in the 1st phase of the wound process allows reducing the time for wound surfaces cleaning as well as the time for treating patients with this pathology in a hospital.
Introduction. Chronic venous insufficiency is one of the most common diseases, so finding the best treatment options is one of the most urgent tasks of surgery. One of the methods of implementing this direction is to apply a personalized approach. The aim of the study is to improve surgical care for patients with VVPC by introducing a personalized approach.Materials and methods. The study was based on clinical observations and special studies in 428 patients with uBVNC in outpatient settings. All of those surveyed were women. The average age of the patients was 42.3 ± 15.5 years. All patients were operated on — endovasal laser coagulation (EVLk) was performed in the traditional way. Clinical examination of patients, as well as special methods of research was carried out. A questionnaire was used to assess the quality of life of patients. The peculiarity of the study was the use of social and hygienic methods: survey, psychological testing, expert. Statistical analysis and mathematical processing of results were carried out with the help of modern computer technologies based on the Statisticala 6 application package.Results. It has been established that over the past five years in the Ivanovo region there has been an increase in the incidence of vessels of the lower extremities. The frequency of varicose veins exceeds 47 per 100 patients examined. The desire to perform surgery in the nonstate health sector is observed in 9.8 cases. In 85.0% of patients with VBNC, received for surgical treatment, have a lack of preparedness. Their information, clinical and psychological level is 65.0–89.0% of the due and direct influence on the formation of an unfavorable result.Conclusion. Thus, the implementation of a personalized approach to the surgical treatment of patients with chronic venous insufficiency by laser coagulation provides on a par with the reliable obliteration of altered veins the fastest clinical recovery of patients, improvement of their quality of life, satisfaction with results, good hemodynamic and cosmetic effects.
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