The experimental production of hemorrhagic lesions in the rat adrenal, liver and lung by basic polyglutamic acid derivatives

Lázár, G.; Szabó, Sándor; Husztik, E.

doi:10.1007/bf01852142

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/ Cns-depressants1

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1975

1989

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Cited by 6 publications

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“…It was also established that spironolactone delays the development and diminishes the incidence of mammary tumors induced by DMBA (Kovacs & Somogyi, 1970). Adrenal apoplexy produced by basic polyglutamic acids is not influenced by PCN, ethylestrenol or triamcinolone; only spironolactone offers some protection (Lazar et al, 1972).…”

Section: / Cns-depressantsmentioning

confidence: 99%

Effect of ACTH, corticoids and PCN (pregnenolone-16α-carbonitrile) on drug responses and disposition

Szabó¹

1979

Acta Endocrinologica

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The endocrine system plays an important role in the adaptation of the organism to environmental stimuli: it influences both specific and nonspecific responses. The ,,emergency reaction" and the ,,stress syndrome" were recognized a long time ago, but they remain very complex processes. Elucidation of their mechanism(s) of action is difficult, and the importance of individual hormones is not yet clearly understood. extracts and corticosterone, but not by DOC (Jensen & Grattan, 1940).

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Section: / Cns-depressantsmentioning

confidence: 99%