“…These similarities could facilitate substitution of smoking with vaping. Indeed, several studies suggest that ECs may function as a substitute for cigarettes in laboratory settings (Grace, Kivell, & Laugesen, ; Johnson, Johnson, Rass, & Pacek, ; Pope et al, ; Quisenberry, Koffarnus, Epstein, & Bickel, ; Quisenberry, Koffarnus, Hatz, Epstein, & Bickel, ; Snider, Cummings, & Bickel, ; Stein, Koffarnus, Stepanov, Hatsukami, & Bickel, ), and a small number of randomized controlled studies suggest that vaping may promote smoking cessation (Adriaens, Van Gucht, Declerck, & Baeyens, ; Bullen et al, ; Caponnetto et al, ). Another reason to favor a transition to ECs for smokers is that ECs contain fewer toxicants and carcinogens than cigarettes (Goniewicz et al, ; Shahab et al, ).…”