The expression of parental fear-conditioned memory in the hippocampal neurons of subsequent progeny

Abstract

This paper researches the concept of parental fear-conditioned memory and its potential transmission to subsequent generations, focusing on examining whether memory traces formed in the hippocampus CA3 region of parents are retained in the hippocampus of their offspring. Through experiments conducted on mice, it is expected that the findings will reveal how fear conditioning in the parental generation impacts the behavioral sensitivity and neuroanatomical changes in the hippocampal neurons of the offspring. The study explores the potential inheritance of transgenerational memory from parents to children and the specific brain sites involved.