The Expression of SIRT1 in Ocular Tissues

Abstract

SIRT1 is a nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase which regulates many physiological and pathological processes. Over the past decade, increasing attention has been paid to the wide distribution of SIRT1 in the eye and its important role in eye development. The short review summarized the most recent research in the study of SIRT1 related to eye development and its distribution in eye.