Ultrasound technology is available in many pediatric perioperative settings. There is an increasing number of ultrasound applications for anesthesiologists which may enhance clinical performance, procedural safety, and patient outcomes. This review highlights the literature and experience supporting focused ultrasound applications in the pediatric perioperative setting across varied disciplines including anesthesiology. The review also suggests strategies for building educational and infrastructural systems to translate this technology into clinical practice. K E Y W O R D S anesthesiology, echocardiography, education, nerve block, patient safety, ultrasonography | 673 CONLON et aL. How to cite this article: Conlon TW, Lin EE, Bruins BB, et al. Getting to know a familiar face: Current and emerging focused ultrasound applications for the perioperative setting. Pediatr