The extraction, enrichment, and highly sensitive determination techniques based on new separation media

Abstract

The extraction, enrichment, and highly sensitive determination of trace components in complex matrices has always been a difficult and hot issue in the field of analytical chemistry, involving environmental pollution monitoring, food and drug safety analysis, and biological sample determination, which is related to human health closely. It is necessary to extract, separate, purify, and enrich trace target components in order to achieve highly sensitive and accurate determination. Therefore, sample pretreatment technique is a key procedure in the analysis of trace components. The core of most sample pretreatment techniques is the selection and optimization of separation medium, and the physical and chemical properties, such as the functional group composition and morphology structure of the separation medium, have important effects on its adsorption and extraction performance. This review summarizes the current progress of two major types of separation media, granular separation medium and monolithic separation medium, and the extraction, enrichment, and highly sensitive determination techniques based on new separation media, as well as their applications in the fields of environmental analysis, food analysis, biological analysis and pharmaceutical analysis.