The eyes of parents on infants awakening

Giganti, Fiorenza; Toselli, Monica

doi:10.1075/aicr.38.14gig

Cited by 3 publications

(3 citation statements)

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“…However, infants who were parentally defined as having a sleep problem were significantly more likely still to be breastfeeding 28–30 . Breastfeeding has been reported to be associated with more time spent awake at night, faster digestion of breast milk, as well as the development of poorer habits with regards to routine sleep timing, self‐soothing behaviors, and parenting style, rather than malnutrition per se 31 . Breastfeeding at the age of 1 year has also been identified as a risk factor for the persistence of sleep problems into childhood, 30 possibly due to increased parental presence at bedtime, increasing the chances of sleep onset association problems 32 .…”

Section: Discussionmentioning

confidence: 99%

Factors differentiating infants identified by parents as problem sleepers, and those that are not

Gibson

Gander

Elder

2011

Sleep and Biological Rhythms

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Sleep problems are common during infancy. Possible factors which contribute to parental perception of problem sleep were investigated as part of a pilot study collecting objective data on the sleep of 1-year-old New Zealand infants (n = 52 families). Sleep of each infant was monitored for a week at home (ankle actigraphy and sleep diaries, which also included daily infant mood ratings) and parents completed questionnaires addressing their infant's sleep, the living and sleeping environment, and feeding. Thirty-five percent of the infants were considered by parents to have a sleeping problem. These infants had shorter night-time sleep as measured by actigraphy (median = 10.0 h vs 10.7 h for non-problem sleepers [U = 193.0, P < 0.05]), less total sleep per 24 h (median = 11.4 h vs 12.5 h [U = 169.5, P < 0.01]), and were put to bed more often per 24 h (median = 3.5 times vs 3.0 times [U = 201.5, P < 0.05]). Problem sleepers were also more likely to spend Ն 20 min awake at night (68% vs 32% [c 2 = 16.78, P < 0.001]), as well as currently being breastfed (55% vs 45% [c 2 = 5.97, P < 0.05]), and to have moderate-bad mood at bedtime (59% vs 41% [c 2 = 6.54, P < 0.05]). Sleep was also related to parent's diary ratings of their infant's mood and temperament. This study highlights factors contributing to parental perception of problem sleep which is vital for recognizing and managing such problems throughout infancy.

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Section: Discussionmentioning

confidence: 99%

Factors differentiating infants identified by parents as problem sleepers, and those that are not

Gibson

Gander

Elder

2011

Sleep and Biological Rhythms

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“…Some authors have categorised children as 'good' or 'bad' sleepers on the basis of parent-report (or, less often, self-report) of sleep being a 'problem'. Such an approach has merit in detecting the subjective evaluation of sleep but, as already intimated, the variability of factors which may influence this judgement makes it difficult to compare groups of children or to identify which aspects of the child's sleep pattern might be particularly disruptive (Scher, 2002, Giganti & Toselli, 2002. Further, as the study by Sadeh et al, (2003) elegantly demonstrated, 'adequate sleep' cannot simply be defined in terms of an absence of reported difficulty with sleeplessness; in that study even children without reported sleeplessness problems performed better on some tests of neurobehavioural functioning following increased sleep.…”

Section: 3mentioning

confidence: 99%

Are Children Getting Enough Sleep? Implications for Parents

Wiggs

2007

Sociological Research Online

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Sleeping is a child's primary activity; by the time an average child goes to school they will have spent more time sleeping than engaging in any other activity, such as playing, eating or interacting socially. Disturbances of sleep (especially sleeplessness) are one of the most frequent child behaviour problems to be reported by parents, affecting about 30% of typically developing children and adolescents. The definition of ‘sleeplessness problems’ will be considered noting how, with child sleeplessness, the complainant and the sufferer are frequently not the same person (frequently parents are the former and the children the latter), and that this has implications for how we should define and, where appropriate, attempt to ‘treat’ these problems. Parental perceptions and parental sleep patterns, moreover, may be key in understanding how some child sleeplessness problems are conceptualised, how they might impact on the child and family and the mechanisms by which successful intervention for childhood sleeplessness may result in benefits for families. The author suggests that child sleeplessness might be better theoretically conceptualised as comprising two distinct states with different causes and effects. Firstly, a ‘biologically-defined sleeplessness‘ characterised by a child having objectively impaired sleep quantity and/or quality, relative to their biological sleep needs. Secondly, a ‘socially-defined sleeplessness’ characterised by the child's sleep pattern deviating from a desired sleep pattern. Judgements about what constitutes a ‘desired’ sleep pattern will be influenced by multiple factors including expectations and culture. Both of these states may exist independently, or co-exist. Both of these states must be considered in order to decide whether or not children are getting enough sleep.

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“…insights into the polypharmacology of EP3 as ap otential anticancer target, especially in the context of the cytoskeletal effects of drugs. [26] This outcome offers afresh perspective on natural-product-inspired drug discovery,i nw hich an atural product serves as as tarting point, rather than as an actual drug, for the discovery of disease-relevant targets,t argetligand relationships,a nd innovative lead compounds.…”

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confidence: 99%

Deorphaning the Macromolecular Targets of the Natural Anticancer Compound Doliculide

et al. 2016

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The cyclodepsipeptide doliculide is a marine natural product with strong actin-polymerizing and anticancer activities. Evidence for doliculide acting as a potent and subtype-selective antagonist of prostanoid E receptor 3 (EP3) is presented. Computational target prediction suggested that this membrane receptor is a likely macromolecular target and enabled immediate in vitro validation. This proof-of-concept study demonstrates the in silico deorphanization of phenotypic screening hits as a viable concept for future natural-product-inspired chemical biology and drug discovery efforts.

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The eyes of parents on infants awakening

Cited by 3 publications

References 0 publications

Factors differentiating infants identified by parents as problem sleepers, and those that are not

Factors differentiating infants identified by parents as problem sleepers, and those that are not

Are Children Getting Enough Sleep? Implications for Parents

Deorphaning the Macromolecular Targets of the Natural Anticancer Compound Doliculide

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