The fallacy of functional nomenclature in the kingdom of biological multifunctionality: physiological and evolutionary considerations on ion channels
Luca Munaron,
Giorgia Chinigò,
Giorgia Scarpellino
et al.
Abstract:Living organisms are multiscale complex systems that have evolved high degrees of multifunctionality and redundancy in the structure–function relationship. A number of factors, only in part determined genetically, affect the jobs of proteins. The overall structural organization confers unique molecular properties that provide the potential to perform a pattern of activities, some of which are co‐opted by specific environments. The variety of multifunctional proteins is expanding, but most cases are handled ind… Show more
The peer review history is available in the Supporting Information section of this article (https://doi.org/10.1113/ JP284432#support-information-section).
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