R&D teams' internationalization attracts interests from different research-streams. However,the decision on what type of R&D structure is more convenient toinvest in may differ, based on several factors, such as risktaking propensity and internal resource availability. With an aim to enrich the extant literature and to provide practical insights for managers working in the wine industry, this case study exploresthe determinants of an Italian family-owned winery that attempts to keep a balance between its internal and external R&D teams' decision, using an integrated theoretical framework based on the transaction costs and the resource-based view theory. The optimal R&D solution based on an accurate costs vs benefits analysis leads the firm to hire highly qualified staff to manage its internal R&Dunit, as well as to complement the unit with complementary resource that can be accessed through external R&D knowledge sources.