1991
DOI: 10.2106/00004623-199173080-00003
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The fate of cancellous and cortical bone after transplantation of fresh and frozen tissue-antigen-matched and mismatched osteochondral allografts in dogs.

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Cited by 156 publications
(70 citation statements)
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“…1 Autograft has major disadvantages that are well documented and include donor site morbidity, increased operative time, blood loss, and often limited quantity, 2-4 whereas allograft can expose patients to viral contaminations and complications, such as infections, 5 fractures, 6 or intense immune response. [7][8][9] For clinical bone transplantations, tissue-engineering techniques based on the delivery of cells to the defect through the use of three-dimensional porous materials are being investigated.…”
Section: Introduction Bmentioning
confidence: 99%
“…1 Autograft has major disadvantages that are well documented and include donor site morbidity, increased operative time, blood loss, and often limited quantity, 2-4 whereas allograft can expose patients to viral contaminations and complications, such as infections, 5 fractures, 6 or intense immune response. [7][8][9] For clinical bone transplantations, tissue-engineering techniques based on the delivery of cells to the defect through the use of three-dimensional porous materials are being investigated.…”
Section: Introduction Bmentioning
confidence: 99%
“…9,10 Freezing of the graft has been thought to reduce the immune responses, but the procedure interferes with the process of incorporation. 11,12 Animal models have been developed, [13][14][15][16][17] but only limited conclusions can be drawn from these studies. Grafts have been implanted in heterotopic sites, 18 in orthotopic unstable sites, 19 or in orthotopic non-weight-bearing sites.…”
mentioning
confidence: 99%
“…O método de fixação do aloimplante com placa de compressão dinâmica (PCD) e parafusos foi escolhido por ser amplamente utilizado em medicina veterinária nas cirurgias de preservação do membro (LaRUE et al, 1989;MORELLO et al, 2001;BURACCO et al, 2002;BOSTON et al, 2007) e nas de fixação de implantes ósseos (SINIBALDI, 1989;ALIEVI et al, 2007;FERREIRA, 2008), fornecendo adequada estabilidade biomecânica ao membro, associada à compressão das interfaces implante/osso receptor, situações fundamentais para a incorporação ocorrer (STEVENSON et al, 1991;ALIEVI et al, 2007).…”
Section: Resultsunclassified