The Female Genital System

Kennedy, P. C.

doi:10.1016/b978-0-12-391607-5.50012-1

Cited by 152 publications

(164 citation statements)

References 199 publications

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“…Occuring as a consequence of not opening the birth canal, fetal death, placental fluid absorption, progressive dehydration of the dead foetus, with fetal membrane adhesion to the dehydrated fetuses without fetal expulsion (Johnston e Raksil, 1987;Johnston et al, 2001a;Nascimento and Santos, 2003;Jackson, 2004a,b;Grunert et al, 2005;Kennedy and Miller, 2007;Linde-Forsberg, 2010). …”

Section: Discussionmentioning

confidence: 99%

“…The placental fluids are absorbed and the fetal membranes adhere to the dehydrated fetus, allowing the formation of a dark tissue with a wet surface without odor or secretions (Johnston and Raksil, 1987;Johnston et al, 2001a;Nascimento and Santos, 2003;Jackson, 2004b;Grunert et al, 2005;Kennedy and Miller, 2007). This is a rare condition described secondary of impaired blood flow to the placenta and umbilical cord due to cord or uterine torsion, trauma, transplacental infections, toxins in the maternal diet or placental dysfunction.…”

Section: Discussionmentioning

confidence: 99%

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Mummified papyraceous fetuses in the abdominal cavity of an elderly female dog with pyometra

Voorwald¹,

Tiosso²,

Cardilli³

et al. 2012

Arq. Bras. Med. Vet. Zootec.

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This paper reports on a rare case of fetal papyraceous mummification after asymptomatic uterine rupture in an elderly female dog with pyometra. The patient had a history of mating six months before the examination but no apparent signs of gestation or parturition. Exploratory laparotomy was used to identify a rupture of the left uterine horn and the presence of cystic endometrial hyperplasia and pyometra. Two mummified papyraceous fetuses were observed in the abdominal cavity and had adhered to the spleen, pancreas, intestine and omentum. Ovariehysterectomy and corrective surgery were performed. The patient had remained healthy after uterine rupture until a new estrous cycle and the development of pyometra. Bitches that are 10 years old or more are predisposed to implantation failure, pregnancy or parturition problems and they should not be breed to avoid complications.Keywords: bitch, uterine rupture, fetal mummification, papyraceous RESUMO Relatou-se um caso raro de mumificação fetal papirácea após ruptura uterina assintomática em uma cadela idosa, acometida por piometra. A paciente apresentava histórico de cópula seis meses antes do

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Mummified papyraceous fetuses in the abdominal cavity of an elderly female dog with pyometra

Voorwald¹,

Tiosso²,

Cardilli³

et al. 2012

Arq. Bras. Med. Vet. Zootec.

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“…Unruptured follicles observed at estrus stage are developing to luteinized cysts at normal metestrus in normal cycling rats. In the normal metestrus phase, howevadvanced luteinization from a cystic corpora lutea formed after regular ovulation (Kennedy and Miller, 1993) if an ovum is not present on the specimen. Therefore, for precise histopathological examination of the female reproductive organs, it is desirable to evaluate each phase so that each particular change can be delineated.…”

Section: Discussionmentioning

confidence: 99%

Collaborative work on evaluation of ovarian toxicity 12) Effects of 2- or 4-week repeated dose studies and fertility study of indomethacin in female rats

et al. 2009

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-2-week and 4-week general toxicity studies of indomethacin, a nonselective inhibitor of cyclooxygenase 1 and 2, were performed using rats. A female fertility study was also conducted to comto assess whether a precise histopathological examination, taking the morphological changes the female reproductive organs undergo during each estrus phases into account, can evaluate toxicity to the ovaries, and to determine the optimal administration period for detecting ovarian toxicity. Indomethacin was administered on a daily basis to female Sprague-Dawley rats at doses of 0, 0.4, 1.3, or 4 mg/kg in the both the general toxicity studies and the female fertility study. In the general toxicity studies, unruptured follicles or luteinized cysts were observed histopathologically in the 4 mg/kg group in both the 2-week and 4-week studies. In addition, follicular cysts were found in the 4 mg/kg group in the 4-week study. Estrous cyclicity was not disturbed in both studies. There were no histopathological changes in the ovaries of the 1.3 mg/kg group in general toxicity studies. In the female fertility study, no toxic effects on female fertility parameters were detected in the 0.4 and 1.3 mg/kg group treated with indomethacin, but 8 of 10 rats in -in the ovary. In addition, 4 weeks of dosing maybe required for induction of follicular cysts, although we could not clearly show that these histopathological changes would affect female fertility functions. These present studies suggest that a precise histopathological examination may be able to predict the effect of test articles on female reproductive functions.

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“…[12][13][14] In ruminants, estrogen is usually involved in the pathogenesis of CEH. 9,10 This case report describes a case of endometritis and CEH in a goat.…”

mentioning

confidence: 99%

“…This may lead to retention and persistence of the corpora lutea and increased progesterone levels with persistent uterine infection. 9 Cystic endometrial hyperplasia has also been described in association with pituitary adenoma and Central Nervous System (CNS) signs in a goat. 11 No CNS signs were reported in this case.…”

mentioning

confidence: 99%

Endometritis and Cystic Endometrial Hyperplasia in a Goat

Radi

2005

J VET Diagn Invest

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Abstract. Histologic examination was performed on uterine biopsy samples of irregular cystic masses noted during caesarean section of a 2-year-old female Boer goat. Histopathologic examination revealed multifocal erosions of the superficial epithelium and multifocal infiltration of the endometrium by widely scattered viable and degenerate neutrophils, lymphocytes, and plasma cells admixed with mild amounts of cellular debris and hemorrhage. The endometrium was markedly expanded by many irregular cystic and hyperplastic glands. This is the first case report of endometritis and cystic endometrial hyperplasia in a goat in North America.

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The Female Genital System

Cited by 152 publications

References 199 publications

Mummified papyraceous fetuses in the abdominal cavity of an elderly female dog with pyometra

Mummified papyraceous fetuses in the abdominal cavity of an elderly female dog with pyometra

Collaborative work on evaluation of ovarian toxicity 12) Effects of 2- or 4-week repeated dose studies and fertility study of indomethacin in female rats

Endometritis and Cystic Endometrial Hyperplasia in a Goat

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