2013
DOI: 10.1016/j.ajog.2013.08.030
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The fetal inflammatory response syndrome is a risk factor for morbidity in preterm neonates

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Cited by 104 publications
(111 citation statements)
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“…Based on the trajectory of white matter development, inflammation in fetal life (termed fetal inflammatory response syndrome) and in the first 2 postnatal years would have the greatest effect on white matter. 68 Neurobehavioral consequences of inflammationinduced hypomyelination include poorer connectivity and slower speed of processing.…”
Section: Assessment Of Nutritionmentioning
confidence: 99%
“…Based on the trajectory of white matter development, inflammation in fetal life (termed fetal inflammatory response syndrome) and in the first 2 postnatal years would have the greatest effect on white matter. 68 Neurobehavioral consequences of inflammationinduced hypomyelination include poorer connectivity and slower speed of processing.…”
Section: Assessment Of Nutritionmentioning
confidence: 99%
“…23 Hoffer compared the correlation between FIRS and adverse neonatal outcome between neonates less than 32 weeks' GA with neonates 32 weeks or longer, it shows nearly significant result (P= 0.065). 27 In our prediction model, the combination of leukocyte counts and GA at PPROM increased the AUC, from 0.68 and 0.81 respectively as sole predictors, to 0.82 for final model to predict BA (Figure 1-3). However, in model simulation, the highest probability of BA was 40.73 percent.…”
Section: Discussionmentioning
confidence: 99%
“…25 Moreover, it was associated with adverse neonatal outcomes including intraventricuar hemorrhage, early-onset sepsis, bronchopulmonary dysplasia, death, and RDS. 26,27 In our study, 12,450/mm3 is the cutoff point to predict BA (AUC 0.68, 95%CI 0.57-0.80, Sensitivity 46.7%, Specificity 88%). In addition, Gibbs, et al found 15,750/mm 3 as significant mean level correlated with intraamniotic infection.…”
Section: Discussionmentioning
confidence: 99%
“…Taip pat TNF-α, IL-1β ir IL-8 aktyvina IL-6 sekreciją decidualinės plokštelės ir choriono membranos ląstelėse [31]. Tuo tarpu IL-6 įvardi-jamas kaip ūmios uždegimo atsako fazės žymuo, skatinantis ūmios fazės reaktantų, pvz., C-reaktyvaus baltymo, gamybą kepenyse, o padidėjusi IL-6 koncentracija vaisiaus virkštelės kraujyje yra vaisiaus uždegiminio atsako sindromo apibrėži-mo sudedamoji dalis [32,33]. Taip pat padidėjusios IL-1β ir IL-8 koncentracijos gimdos apatiniame segmente sieja-teorija ir praktika 2015 -T. 21 (Nr.…”
Section: įVadasunclassified