The Fibrin Glue Application Enhances Surgical Success Rate in Endonasal Endoscopic Dacryocystorhinostomy With Lacrimal Sac Preservation

Ceylan, Seyit Mehmet; Erdoğan, Ceren; Sözen, Tevfik; Kanmaz, Mahmut Alper; Disikirik, Ilyas; Jafarov, Shamkhal; Tahir, Emel

doi:10.1177/0145561319882123

Cited by 11 publications

(11 citation statements)

References 31 publications

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“…In this study, mitomycin-C was applied to 22% patients whereas in study conducted by Priya et al mitomycin was applied in 51% cases to see the effect of intraoperative topical application of mitomycin-C during EEDCR surgical procedure. 11 Kulkarni et al conducted a study to compare the endonasal dacryocystorhinostomy with and without adjunctive topical use of mitomycin C. 8 He found that synechiae formation was seen in 16% and granulation formation was seen in 6% which is higher than our study. It was found that there is no significant relationship between mitomycin applied and rate of surgical success (Table 6).…”

Section: Discussioncontrasting

confidence: 65%

“…Priya et al conducted a study in which success rate of EEDCR at the end of 3 months was 100%. 11 This was maintained till 6 months with a fall to 97% at the end of 1 year.…”

Section: Discussionmentioning

confidence: 96%

“…10 In present study, 94% patients had given Local anaesthesia with IV sedation and 6% had given GA for EEDCR surgical procedure whereas Priya et al conducted a study to study the EEDCR with special reference to mitomycin-C, the all patients in her study were operated with for local anaesthesia under IV sedation. 11 During EEDCR procedure, in 66% patients, posterior flap was used followed by in 22 % H shaped flap and in 6% inferior flap was used after surgery. It was found that there is no significant relationship between type of flap used and rate of surgical success (Table 5).…”

Section: Discussionmentioning

confidence: 99%

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Endoscopic endonasal dacryocystorhinostomy-an experience in a tertiary care hospital

Gujrathi¹,

Kamble²,

Khadkekar³

et al. 2021

Int J Otorhinolaryngol Head Neck Surg

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Background: Dacryocystorhinostomy is a surgical procedure by which the lacrimal flow is diverted into the nasal cavity by making an opening in the lacrimal sac when the nasolacrimal duct gets blocked. The operation can be carried out using either an external or endonasal surgical approach.Methods: This is a clinical observational study done on 50 patients with chronic dacryocystitis with obstruction at the level of sac or nasolacrimal duct. This study was conducted at Dr. Shankarrao Chavan government medical college, Nanded, during the period of 2 years (2018-2020). Patients were evaluated and operated for endoscopic endonasal dacryocystorhinostomy.Results: The mean age of studied cases was 33.92±12.13 years. The M:F ratio was 0.78. Epiphora was the predominant complaint in all cases 100%. Swelling of lacrimal sac was present in 24% cases and Pain on affected side was present in 18% cases. 6% patients had fistula on the side of block. 12% patients had mucocele and 14% patients had pyocele on the affected side. Left and right side was involved in 54% and 40% cases respectively. The disease presented bilaterally in 06% cases. 80% patients had no complications after endonasal endoscopic dacryocystorhinostomy (EEDCR) surgery. Rate of surgical success was 92%.Conclusions: Nasolacrimal duct obstruction is more common among females and in middle aged persons. EEDCR is treatment which provides patients relief from the symptoms without any scar and also preserves nasolacrimal pump system with high success rate. It may prove better surgical technique in chronic dacryocystitis.

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Section: Discussioncontrasting

confidence: 65%

“…Priya et al conducted a study in which success rate of EEDCR at the end of 3 months was 100%. 11 This was maintained till 6 months with a fall to 97% at the end of 1 year.…”

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

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Endoscopic endonasal dacryocystorhinostomy-an experience in a tertiary care hospital

Gujrathi¹,

Kamble²,

Khadkekar³

et al. 2021

Int J Otorhinolaryngol Head Neck Surg

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“…[ 20 21 ] Ceylan SM et al . [ 22 ] used fibrin glue for anastomosing the lacrimal sac and nasal mucosal flaps during endoscopic endonasal DCR and noted a significantly higher success rate in the fibrin glue group compared to the cases where glue was not utilized (95.5% vs. 84.8%). The authors concluded that creation of an anastomosis between the lacrimal sac flaps and the nasal mucosa using fibrin glue improves the outcome of endoscopic endonasal DCR.…”

Section: Discussionmentioning

confidence: 99%

A glued technique of external dacryocystorhinostomy

Rizvi

Sabah

Mehmood

et al. 2022

Indian Journal of Ophthalmology

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Purpose: Fibrin glue was used for anastomosis of lacrimal sac and nasal mucosal flaps and was compared with the conventional suture technique in external dacryocystorhinostomy. Methods: A prospective interventional randomized control study in which 50 consecutive patients of primary acquired nasolacrimal duct obstruction (PANDO) were equally allocated into two groups. The case group underwent glued technique of external dacryocystorhinostomy (Ext DCR) in which fibrin glue was used for the apposition of the anterior lacrimal sac and nasal mucosal flaps. In the control group, conventional technique of Ext DCR was used to suture the flaps. Functional success was assessed by improvement in epiphora and fluorescein dye disappearance test (FDDT), whereas anatomical success was assessed by lacrimal irrigation and endoscopic view of the osteotomy site. Results: The anatomical success in both the groups was 92%, whereas the functional success was 92% in the case group and 88% in the control group. The difference in the success rates between the two groups was statistically non-significant. Conclusion: Glued technique of Ext DCR is a simple and easy alternative to suturing of the flaps. Though the final outcome was comparable in both the groups, glue can be especially useful in uncooperative cases, in cases of excessive bleeding, or in situations where the flaps are very thin or have become friable.

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“…Scientists from the Ahmedabad center tested the viability of human dental pulp stem cells (HDPS) in 2D and 3D fibrin scaffolds of various concentrations. They found that 25% fibrin glue prolongs HDPS viability which may be of great importance for regenerative endodontics [9,[36][37][38][39][40].…”

Section: Other Applications Of Fibrin Gluementioning

confidence: 99%